ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description:
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000028874 Fgr 10090 + 4:132974095-133001910 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000030693 Fgr-001 132974102-133001910 protein_coding
  ENSMUST00000124451 Fgr-003 132974095-132984360 processed_transcript
  ENSMUST00000138179 Fgr-002 132977116-133000767 processed_transcript
  ENSMUST00000171223 Fgr-201 132977116-133000767 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; Tie2+ ECmESENSMUST00000030693ENSMUST00000138179
Transcript ID Tie2+ EC mES
ENSMUST00000030693 0.098±0.07 0.060±0.01
ENSMUST00000138179 0.050±0.01 0.070±0.04

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0008WN CIL_0008WN_0002 VISTA

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001784 IDA phosphotyrosine binding
GO:0004715 IDA non-membrane spanning protein tyrosine kinase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005743 IEA mitochondrial inner membrane
GO:0005829 IEA cytosol
GO:0005856 IEA cytoskeleton
GO:0005886 IDA plasma membrane
GO:0007229 IMP integrin-mediated signaling pathway
GO:0008360 IMP regulation of cell shape
GO:0014068 IEA positive regulation of phosphatidylinositol 3-kinase signaling
GO:0015629 IDA actin cytoskeleton
GO:0018108 IDA peptidyl-tyrosine phosphorylation
GO:0019901 IDA protein kinase binding
GO:0030335 IMP positive regulation of cell migration
GO:0032587 IDA ruffle membrane
GO:0032956 TAS regulation of actin cytoskeleton organization
GO:0034987 IDA immunoglobulin receptor binding
GO:0034988 IEA Fc-gamma receptor I complex binding
GO:0043306 IDA positive regulation of mast cell degranulation
GO:0043552 IEA positive regulation of phosphatidylinositol 3-kinase activity
GO:0045087 IEA innate immune response
GO:0045088 IMP regulation of innate immune response
GO:0045859 IDA regulation of protein kinase activity
GO:0046777 IEA protein autophosphorylation
GO:0050715 IDA positive regulation of cytokine secretion
GO:0050764 IMP regulation of phagocytosis
GO:0050830 IGI defense response to Gram-positive bacterium
GO:0070062 IEA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000000938 FGR FGR proto-oncogene, Src family tyrosine kinase protein_coding Homo_sapiens

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