ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description:
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000030400 Ercc2 10090 + 7:19382010-19395694 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000062831 Ercc2-001 19382010-19395694 protein_coding
  ENSMUST00000108460 Ercc2-003 19382040-19395694 protein_coding
  ENSMUST00000108461 Ercc2-002 19382031-19395692 protein_coding
  ENSMUST00000127363 Ercc2-006 19382208-19385893 processed_transcript
  ENSMUST00000128167 Ercc2-007 19388203-19393680 processed_transcript
  ENSMUST00000129249 Ercc2-004 19382269-19394461 protein_coding
  ENSMUST00000129291 Ercc2-008 19390396-19391906 retained_intron
  ENSMUST00000135693 Ercc2-009 19393430-19394786 retained_intron
  ENSMUST00000136055 Ercc2-005 19382018-19385688 processed_transcript
  ENSMUST00000145039 Ercc2-010 19393661-19394065 retained_intron

Expression Patterns


Heat Map
Numeric Values
Transcript'; C166Tie2+ ECmESENSMUST00000062831ENSMUST00000108460ENSMUST00000108461ENSMUST00000129249
Transcript ID C166 Tie2+ EC mES
ENSMUST00000062831 7.244±0.89 2.469±1.52 1.534±0.17
ENSMUST00000108460 N/A 1.038±0.74 N/A
ENSMUST00000108461 N/A N/A 3.281±0.15
ENSMUST00000129249 4.140±0.15 0.527±0.00 N/A

Conserved Regions

Not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000439 IEA core TFIIH complex
GO:0001666 IEA response to hypoxia
GO:0001701 IMP in utero embryonic development
GO:0003677 IEA DNA binding
GO:0004003 IEA ATP-dependent DNA helicase activity
GO:0004672 ISS protein kinase activity
GO:0005515 IEA protein binding
GO:0005524 IEA ATP binding
GO:0005634 IDA nucleus
GO:0005675 ISS holo TFIIH complex
GO:0005737 ISS cytoplasm
GO:0005819 ISS spindle
GO:0006200 IEA ATP catabolic process
GO:0006281 IMP DNA repair
GO:0006283 ISS transcription-coupled nucleotide-excision repair
GO:0006289 IMP nucleotide-excision repair
GO:0006366 ISS transcription from RNA polymerase II promoter
GO:0006468 IEA protein phosphorylation
GO:0006915 ISS apoptotic process
GO:0006979 IMP response to oxidative stress
GO:0007059 ISS chromosome segregation
GO:0007568 IMP aging
GO:0008022 IEA protein C-terminus binding
GO:0008094 ISS DNA-dependent ATPase activity
GO:0008283 IMP cell proliferation
GO:0008353 ISS RNA polymerase II carboxy-terminal domain kinase activity
GO:0009411 IMP response to UV
GO:0009650 IMP UV protection
GO:0009791 IMP post-embryonic development
GO:0019907 IEA cyclin-dependent protein kinase activating kinase holoenzyme complex
GO:0021510 IMP spinal cord development
GO:0022405 IMP hair cycle process
GO:0030198 IMP extracellular matrix organization
GO:0030282 IMP bone mineralization
GO:0032289 IMP central nervous system myelin formation
GO:0032508 IEA DNA duplex unwinding
GO:0033683 IEA nucleotide-excision repair, DNA incision
GO:0035264 IMP multicellular organism growth
GO:0035315 IMP hair cell differentiation
GO:0040016 IMP embryonic cleavage
GO:0043139 ISS 5'-3' DNA helicase activity
GO:0043249 IMP erythrocyte maturation
GO:0043388 IMP positive regulation of DNA binding
GO:0043588 IMP skin development
GO:0045893 IEA positive regulation of transcription, DNA-templated
GO:0045944 IEA positive regulation of transcription from RNA polymerase II promoter
GO:0046872 IEA metal ion binding
GO:0047485 IEA protein N-terminus binding
GO:0048820 IMP hair follicle maturation
GO:0051539 IEA 4 iron, 4 sulfur cluster binding
GO:0060218 IMP hematopoietic stem cell differentiation
GO:0071817 ISS MMXD complex
GO:1901990 IEA regulation of mitotic cell cycle phase transition

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000021985 ercc2 protein_coding Danio_rerio
ENSG00000104884 ERCC2 excision repair cross-complementation group 2 protein_coding Homo_sapiens

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