ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Transcript Info
Description:
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000062831 Ercc2-001 ENSMUSG00000030400 10090 + 7:19382010-19395694 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; C166Tie2+ ECmESENSMUST00000062831
Transcript ID C166 Tie2+ EC mES
ENSMUST00000062831 7.244±0.89 2.469±1.52 1.534±0.17

Conserved Regions

Not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000439 IEA core TFIIH complex
GO:0001666 IEA response to hypoxia
GO:0001701 IMP in utero embryonic development
GO:0003677 IEA DNA binding
GO:0004003 IEA ATP-dependent DNA helicase activity
GO:0004672 ISS protein kinase activity
GO:0005515 IEA protein binding
GO:0005524 IEA ATP binding
GO:0005634 IDA nucleus
GO:0005675 ISS holo TFIIH complex
GO:0005737 ISS cytoplasm
GO:0005819 ISS spindle
GO:0006200 IEA ATP catabolic process
GO:0006281 IMP DNA repair
GO:0006283 ISS transcription-coupled nucleotide-excision repair
GO:0006289 IMP nucleotide-excision repair
GO:0006366 ISS transcription from RNA polymerase II promoter
GO:0006468 IEA protein phosphorylation
GO:0006915 ISS apoptotic process
GO:0006979 IMP response to oxidative stress
GO:0007059 ISS chromosome segregation
GO:0007568 IMP aging
GO:0008022 IEA protein C-terminus binding
GO:0008094 ISS DNA-dependent ATPase activity
GO:0008283 IMP cell proliferation
GO:0008353 ISS RNA polymerase II carboxy-terminal domain kinase activity
GO:0009411 IMP response to UV
GO:0009650 IMP UV protection
GO:0009791 IMP post-embryonic development
GO:0019907 IEA cyclin-dependent protein kinase activating kinase holoenzyme complex
GO:0021510 IMP spinal cord development
GO:0022405 IMP hair cycle process
GO:0030198 IMP extracellular matrix organization
GO:0030282 IMP bone mineralization
GO:0032289 IMP central nervous system myelin formation
GO:0032508 IEA DNA duplex unwinding
GO:0033683 IEA nucleotide-excision repair, DNA incision
GO:0035264 IMP multicellular organism growth
GO:0035315 IMP hair cell differentiation
GO:0040016 IMP embryonic cleavage
GO:0043139 ISS 5'-3' DNA helicase activity
GO:0043249 IMP erythrocyte maturation
GO:0043388 IMP positive regulation of DNA binding
GO:0043588 IMP skin development
GO:0045893 IEA positive regulation of transcription, DNA-templated
GO:0045944 IEA positive regulation of transcription from RNA polymerase II promoter
GO:0046872 IEA metal ion binding
GO:0047485 IEA protein N-terminus binding
GO:0048820 IMP hair follicle maturation
GO:0051539 IEA 4 iron, 4 sulfur cluster binding
GO:0060218 IMP hematopoietic stem cell differentiation
GO:0071817 ISS MMXD complex
GO:1901990 IEA regulation of mitotic cell cycle phase transition

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000391941 ERCC2-005 protein_coding Homo_sapiens 0 2739
ENST00000391942 ERCC2-007 retained_intron Homo_sapiens 0 1487
ENST00000391944 ERCC2-201 protein_coding Homo_sapiens 0 2141
ENST00000391945 ERCC2-001 protein_coding Homo_sapiens 0 2861
ENST00000391946 KLC3-001 protein_coding Homo_sapiens 1e-18 99
ENST00000470402 KLC3-002 protein_coding Homo_sapiens 1e-18 99
ENST00000485403 ERCC2-006 protein_coding Homo_sapiens 0 1504
ENST00000585434 KLC3-004 protein_coding Homo_sapiens 1e-18 99
ENST00000586131 ERCC2-002 protein_coding Homo_sapiens 0 1134
ENST00000586441 ERCC2-010 retained_intron Homo_sapiens 0 464
ENST00000586856 ERCC2-003 protein_coding Homo_sapiens 5e-39 165
ENST00000587376 ERCC2-004 nonsense_mediated_decay Homo_sapiens 0 785
ENST00000588652 ERCC2-008 retained_intron Homo_sapiens 0 1260
ENST00000589373 KLC3-005 protein_coding Homo_sapiens 0.000000005 68
ENST00000591309 ERCC2-011 nonsense_mediated_decay Homo_sapiens 0 462

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