ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description:
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000031523 Dlc1 10090 - 8:36567751-36953143 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000033923 Dlc1-002 36567751-36613943 protein_coding
  ENSMUST00000036104 Dlc1-006 36849126-36952357 retained_intron
  ENSMUST00000098826 Dlc1-001 36567751-36733054 protein_coding
  ENSMUST00000145245 Dlc1-003 36593231-36613874 retained_intron
  ENSMUST00000156312 Dlc1-004 36572145-36577269 retained_intron
  ENSMUST00000163663 Dlc1-005 36570249-36952442 protein_coding
  ENSMUST00000178717 Dlc1-007 36857711-36952422 retained_intron
  ENSMUST00000179501 Dlc1-009 36938555-36953143 protein_coding
  ENSMUST00000179652 Dlc1-008 36935584-36952436 retained_intron

Expression Patterns


Heat Map
Numeric Values
Transcript'; C166Tie2+ ECmESENSMUST00000033923
Transcript ID C166 Tie2+ EC mES
ENSMUST00000033923 4.993±0.40 81.132±60.34 11.266±1.37

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0003VG CIL_0003VG_0002 CGP
CIL_000274 CIL_000274_0002 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001843 IMP neural tube closure
GO:0003007 IMP heart morphogenesis
GO:0005096 IEA GTPase activator activity
GO:0005100 IEA Rho GTPase activator activity
GO:0005622 IEA intracellular
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0005901 IEA caveola
GO:0005925 IEA focal adhesion
GO:0006915 IEA apoptotic process
GO:0006919 IEA activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0007165 IEA signal transduction
GO:0008285 ISS negative regulation of cell proliferation
GO:0008289 IEA lipid binding
GO:0008360 IEA regulation of cell shape
GO:0016020 IEA membrane
GO:0021575 IMP hindbrain morphogenesis
GO:0030036 IMP actin cytoskeleton organization
GO:0030054 IEA cell junction
GO:0030336 IEA negative regulation of cell migration
GO:0030900 IMP forebrain development
GO:0032321 IEA positive regulation of Rho GTPase activity
GO:0032956 IEA regulation of actin cytoskeleton organization
GO:0035023 IEA regulation of Rho protein signal transduction
GO:0035024 IEA negative regulation of Rho protein signal transduction
GO:0035307 IEA positive regulation of protein dephosphorylation
GO:0042169 IEA SH2 domain binding
GO:0043547 IEA positive regulation of GTPase activity
GO:0048041 IMP focal adhesion assembly
GO:0051497 IEA negative regulation of stress fiber assembly
GO:1900119 IEA positive regulation of execution phase of apoptosis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000079317 DLC1 protein_coding Danio_rerio
ENSG00000164741 DLC1 DLC1 Rho GTPase activating protein protein_coding Homo_sapiens

Loading