ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Transcript Info
Description:
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000036092 Kcnh2-001 ENSMUSG00000038319 10090 - 5:24319589-24351604 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; C166Tie2+ ECmESENSMUST00000036092
Transcript ID C166 Tie2+ EC mES
ENSMUST00000036092 7.310±2.14 0.209±0.22 0.621±0.32

Conserved Regions

Not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000155 IEA phosphorelay sensor kinase activity
GO:0000160 IEA phosphorelay signal transduction system
GO:0005242 IDA inward rectifier potassium channel activity
GO:0005249 IDA voltage-gated potassium channel activity
GO:0005251 IEA delayed rectifier potassium channel activity
GO:0005635 IDA nuclear envelope
GO:0005737 IDA cytoplasm
GO:0005886 IDA plasma membrane
GO:0005887 IBA integral component of plasma membrane
GO:0008076 IEA voltage-gated potassium channel complex
GO:0009986 IEA cell surface
GO:0023014 IEA signal transduction by phosphorylation
GO:0031625 IEA ubiquitin protein ligase binding
GO:0035690 IEA cellular response to drug
GO:0042391 IDA regulation of membrane potential
GO:0042802 IEA identical protein binding
GO:0042803 IEA protein homodimerization activity
GO:0055075 IEA potassium ion homeostasis
GO:0060048 IEA cardiac muscle contraction
GO:0060306 IEA regulation of membrane repolarization
GO:0060307 IDA regulation of ventricular cardiac muscle cell membrane repolarization
GO:0071435 IEA potassium ion export
GO:0071805 IDA potassium ion transmembrane transport
GO:0086005 IEA ventricular cardiac muscle cell action potential
GO:0086010 IEA membrane depolarization during action potential
GO:0086011 IEA membrane repolarization during action potential
GO:0086013 IEA membrane repolarization during cardiac muscle cell action potential
GO:0086091 IDA regulation of heart rate by cardiac conduction
GO:1901379 IEA regulation of potassium ion transmembrane transport
GO:1901380 IEA negative regulation of potassium ion transmembrane transport
GO:1901381 IEA positive regulation of potassium ion transmembrane transport
GO:1902282 IEA voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization
GO:1902303 IEA negative regulation of potassium ion export

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSDART00000024058 kcnh2a-001 protein_coding Danio_rerio 0 881
ENSDART00000090874 KCNH7-201 protein_coding Danio_rerio 0 767
ENSDART00000151288 KCNH7-001 protein_coding Danio_rerio 0 767
ENST00000262186 KCNH2-001 protein_coding Homo_sapiens 0 4865
ENST00000314672 KCNH6-001 protein_coding Homo_sapiens 0 1330
ENST00000330883 KCNH2-004 protein_coding Homo_sapiens 0 3319
ENST00000430723 KCNH2-201 protein_coding Homo_sapiens 0 2263
ENST00000456941 KCNH6-201 protein_coding Homo_sapiens 0 662
ENST00000461280 KCNH2-008 retained_intron Homo_sapiens 0 1736
ENST00000473610 KCNH2-005 retained_intron Homo_sapiens 0 1109
ENST00000532957 KCNH2-002 retained_intron Homo_sapiens 0 3249
ENST00000580652 KCNH6-003 protein_coding Homo_sapiens 0 797
ENST00000581784 KCNH6-002 protein_coding Homo_sapiens 0 662
ENST00000583023 KCNH6-005 protein_coding Homo_sapiens 0 1330
ENST00000583465 KCNH6-004 nonsense_mediated_decay Homo_sapiens 0 1330

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