ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description:
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000041187 Prkd2 10090 + 7:16842902-16870461 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000086104 Prkd2-201 16843065-16870461 protein_coding
  ENSMUST00000168093 Prkd2-202 16842902-16870461 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; C166Tie2+ ECmESENSMUST00000086104ENSMUST00000168093
Transcript ID C166 Tie2+ EC mES
ENSMUST00000086104 1.370±0.35 19.863±8.55 1.795±0.27
ENSMUST00000168093 2.847±0.53 8.834±5.12 4.829±1.79

Conserved Regions

Not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001525 IEA angiogenesis
GO:0001938 ISS positive regulation of endothelial cell proliferation
GO:0004697 IEA protein kinase C activity
GO:0005515 IEA protein binding
GO:0005524 IEA ATP binding
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0005794 IEA Golgi apparatus
GO:0005886 IEA plasma membrane
GO:0007155 IEA cell adhesion
GO:0008219 IEA cell death
GO:0010595 ISS positive regulation of endothelial cell migration
GO:0018105 IEA peptidyl-serine phosphorylation
GO:0030949 ISS positive regulation of vascular endothelial growth factor receptor signaling pathway
GO:0032743 IMP positive regulation of interleukin-2 production
GO:0032757 ISS positive regulation of interleukin-8 production
GO:0032793 IEA positive regulation of CREB transcription factor activity
GO:0033138 IEA positive regulation of peptidyl-serine phosphorylation
GO:0035924 IEA cellular response to vascular endothelial growth factor stimulus
GO:0038033 IEA positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway
GO:0043536 IEA positive regulation of blood vessel endothelial cell migration
GO:0045743 ISS positive regulation of fibroblast growth factor receptor signaling pathway
GO:0045766 ISS positive regulation of angiogenesis
GO:0045785 ISS positive regulation of cell adhesion
GO:0045944 IEA positive regulation of transcription from RNA polymerase II promoter
GO:0046777 IEA protein autophosphorylation
GO:0046872 IEA metal ion binding
GO:0048010 IEA vascular endothelial growth factor receptor signaling pathway
GO:0050852 IEA T cell receptor signaling pathway
GO:0050862 IMP positive regulation of T cell receptor signaling pathway
GO:0051091 ISS positive regulation of sequence-specific DNA binding transcription factor activity
GO:0051092 ISS positive regulation of NF-kappaB transcription factor activity
GO:0070374 IDA positive regulation of ERK1 and ERK2 cascade
GO:1901727 IEA positive regulation of histone deacetylase activity
GO:1902533 IEA positive regulation of intracellular signal transduction
GO:2000573 IDA positive regulation of DNA biosynthetic process
GO:2001028 IEA positive regulation of endothelial cell chemotaxis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000087018 PRKD2 protein_coding Danio_rerio
ENSG00000105287 PRKD2 protein kinase D2 protein_coding Homo_sapiens

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