ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Transcript Info
Description:
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000086104 Prkd2-201 ENSMUSG00000041187 10090 + 7:16843065-16870461 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; C166Tie2+ ECmESENSMUST00000086104
Transcript ID C166 Tie2+ EC mES
ENSMUST00000086104 1.370±0.35 19.863±8.55 1.795±0.27

Conserved Regions

Not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001525 IEA angiogenesis
GO:0001938 ISS positive regulation of endothelial cell proliferation
GO:0004697 IEA protein kinase C activity
GO:0005515 IEA protein binding
GO:0005524 IEA ATP binding
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0005794 IEA Golgi apparatus
GO:0005886 IEA plasma membrane
GO:0007155 IEA cell adhesion
GO:0008219 IEA cell death
GO:0010595 ISS positive regulation of endothelial cell migration
GO:0018105 IEA peptidyl-serine phosphorylation
GO:0030949 ISS positive regulation of vascular endothelial growth factor receptor signaling pathway
GO:0032743 IMP positive regulation of interleukin-2 production
GO:0032757 ISS positive regulation of interleukin-8 production
GO:0032793 IEA positive regulation of CREB transcription factor activity
GO:0033138 IEA positive regulation of peptidyl-serine phosphorylation
GO:0035924 IEA cellular response to vascular endothelial growth factor stimulus
GO:0038033 IEA positive regulation of endothelial cell chemotaxis by VEGF-activated vascular endothelial growth factor receptor signaling pathway
GO:0043536 IEA positive regulation of blood vessel endothelial cell migration
GO:0045743 ISS positive regulation of fibroblast growth factor receptor signaling pathway
GO:0045766 ISS positive regulation of angiogenesis
GO:0045785 ISS positive regulation of cell adhesion
GO:0045944 IEA positive regulation of transcription from RNA polymerase II promoter
GO:0046777 IEA protein autophosphorylation
GO:0046872 IEA metal ion binding
GO:0048010 IEA vascular endothelial growth factor receptor signaling pathway
GO:0050852 IEA T cell receptor signaling pathway
GO:0050862 IMP positive regulation of T cell receptor signaling pathway
GO:0051091 ISS positive regulation of sequence-specific DNA binding transcription factor activity
GO:0051092 ISS positive regulation of NF-kappaB transcription factor activity
GO:0070374 IDA positive regulation of ERK1 and ERK2 cascade
GO:1901727 IEA positive regulation of histone deacetylase activity
GO:1902533 IEA positive regulation of intracellular signal transduction
GO:2000573 IDA positive regulation of DNA biosynthetic process
GO:2001028 IEA positive regulation of endothelial cell chemotaxis

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSDART00000110322 prkd1-201 protein_coding Danio_rerio 0 647
ENSDART00000153937 prkd1-001 protein_coding Danio_rerio 0 647
ENSDART00000112765 prkd3-201 protein_coding Danio_rerio 0 553
ENSDART00000154755 prkd3-001 protein_coding Danio_rerio 0 553
ENST00000291281 PRKD2-001 protein_coding Homo_sapiens 0 3179
ENST00000433867 PRKD2-201 protein_coding Homo_sapiens 0 3179
ENST00000595132 PRKD2-013 protein_coding Homo_sapiens 0 547
ENST00000595515 PRKD2-004 protein_coding Homo_sapiens 0 2867
ENST00000597390 PRKD2-018 nonsense_mediated_decay Homo_sapiens 0 826
ENST00000597589 PRKD2-007 retained_intron Homo_sapiens 0 1690
ENST00000597641 PRKD2-012 nonsense_mediated_decay Homo_sapiens 0 424
ENST00000598633 PRKD2-011 protein_coding Homo_sapiens 0 492
ENST00000599019 PRKD2-008 retained_intron Homo_sapiens 0 1378
ENST00000600194 PRKD2-006 protein_coding Homo_sapiens 0 2896
ENST00000601605 PRKD2-015 protein_coding Homo_sapiens 0 303
ENST00000601806 PRKD2-002 protein_coding Homo_sapiens 0 3053
ENST00000602155 PRKD2-009 retained_intron Homo_sapiens 0 1033

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