ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description:
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000067851 Arfgef1 10090 - 1:10137571-10232670 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000088615 Arfgef1-002 10137571-10232670 protein_coding
  ENSMUST00000128834 Arfgef1-004 10160757-10161306 retained_intron
  ENSMUST00000131556 Arfgef1-001 10173075-10232670 protein_coding
  ENSMUST00000142497 Arfgef1-005 10147405-10154530 retained_intron
  ENSMUST00000156563 Arfgef1-003 10156399-10160060 retained_intron
  ENSMUST00000186720 Arfgef1-007 10209161-10214213 retained_intron
  ENSMUST00000186813 Arfgef1-006 10208946-10210107 retained_intron
  ENSMUST00000187417 Arfgef1-008 10138690-10141701 retained_intron

Expression Patterns


Heat Map
Numeric Values
Transcript'; C166Tie2+ ECmESENSMUST00000088615ENSMUST00000131556
Transcript ID C166 Tie2+ EC mES
ENSMUST00000088615 16.433±1.69 9.544±4.10 7.929±4.09
ENSMUST00000131556 N/A 2.638±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion Type
CIL_0001S0 CIL_0001S0_0003 CGP
CIL_0005BT CIL_0005BT_0003 CGP

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000139 ISS Golgi membrane
GO:0005085 IEA guanyl-nucleotide exchange factor activity
GO:0005086 IBA ARF guanyl-nucleotide exchange factor activity
GO:0005515 IEA protein binding
GO:0005634 IEA nucleus
GO:0005730 ISS nucleolus
GO:0005737 IEA cytoplasm
GO:0005794 IEA Golgi apparatus
GO:0005802 ISS trans-Golgi network
GO:0005829 ISS cytosol
GO:0007030 ISS Golgi organization
GO:0010256 ISS endomembrane system organization
GO:0015031 IEA protein transport
GO:0016192 IBA vesicle-mediated transport
GO:0017022 IEA myosin binding
GO:0030532 ISS small nuclear ribonucleoprotein complex
GO:0030837 ISS negative regulation of actin filament polymerization
GO:0032012 IEA regulation of ARF protein signal transduction
GO:0034237 ISS protein kinase A regulatory subunit binding
GO:0034259 ISS negative regulation of Rho GTPase activity
GO:0043547 IEA positive regulation of GTPase activity
GO:0048471 IEA perinuclear region of cytoplasm
GO:0090284 ISS positive regulation of protein glycosylation in Golgi
GO:0090303 ISS positive regulation of wound healing
GO:2000114 ISS regulation of establishment of cell polarity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000063474 arfgef1 protein_coding Danio_rerio
ENSG00000066777 ARFGEF1 ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited) protein_coding Homo_sapiens

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