ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Transcript Info
Description:
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000000579 Sox9-001 ENSMUSG00000000567 10090 + 11:112782224-112787760 protein_coding

Mus musculus Ensembl GRCm38

Genome
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Expression Patterns


Heat Map
Numeric Values
Transcript'; C166Tie2+ ECmESENSMUST00000000579
Transcript ID C166 Tie2+ EC mES
ENSMUST00000000579 0.901±0.18 1.956±1.43 0.944±0.90

Conserved Regions

Not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 ISO negative regulation of transcription from RNA polymerase II promoter
GO:0000976 IDA transcription regulatory region sequence-specific DNA binding
GO:0000981 IDA sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0001046 ISS core promoter sequence-specific DNA binding
GO:0001077 ISS RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0001158 IDA enhancer sequence-specific DNA binding
GO:0001501 ISS skeletal system development
GO:0001502 IMP cartilage condensation
GO:0001503 IEP ossification
GO:0001658 IEP branching involved in ureteric bud morphogenesis
GO:0001708 IMP cell fate specification
GO:0001837 IMP epithelial to mesenchymal transition
GO:0001894 IMP tissue homeostasis
GO:0001934 IDA positive regulation of protein phosphorylation
GO:0001942 IMP hair follicle development
GO:0002053 IMP positive regulation of mesenchymal cell proliferation
GO:0002062 IEP chondrocyte differentiation
GO:0002063 IMP chondrocyte development
GO:0002683 IMP negative regulation of immune system process
GO:0003170 IMP heart valve development
GO:0003179 IMP heart valve morphogenesis
GO:0003188 IMP heart valve formation
GO:0003203 IMP endocardial cushion morphogenesis
GO:0003413 ISS chondrocyte differentiation involved in endochondral bone morphogenesis
GO:0003415 IMP chondrocyte hypertrophy
GO:0003677 IDA DNA binding
GO:0003682 ISS chromatin binding
GO:0003700 IMP sequence-specific DNA binding transcription factor activity
GO:0003705 IDA RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity
GO:0004672 IMP protein kinase activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005667 IPI transcription factor complex
GO:0006334 ISS nucleosome assembly
GO:0006338 ISS chromatin remodeling
GO:0006355 TAS regulation of transcription, DNA-templated
GO:0006357 IDA regulation of transcription from RNA polymerase II promoter
GO:0006366 IEA transcription from RNA polymerase II promoter
GO:0006461 ISS protein complex assembly
GO:0006468 IMP protein phosphorylation
GO:0007010 IMP cytoskeleton organization
GO:0007165 IMP signal transduction
GO:0007173 IDA epidermal growth factor receptor signaling pathway
GO:0007283 IGI spermatogenesis
GO:0007417 IEP central nervous system development
GO:0007507 IMP heart development
GO:0008013 IPI beta-catenin binding
GO:0008284 IMP positive regulation of cell proliferation
GO:0008285 IMP negative regulation of cell proliferation
GO:0008584 IMP male gonad development
GO:0010564 ISS regulation of cell cycle process
GO:0010628 IGI positive regulation of gene expression
GO:0010634 ISS positive regulation of epithelial cell migration
GO:0014032 IMP neural crest cell development
GO:0014068 IMP positive regulation of phosphatidylinositol 3-kinase signaling
GO:0016337 IMP single organismal cell-cell adhesion
GO:0019100 IMP male germ-line sex determination
GO:0019933 ISS cAMP-mediated signaling
GO:0030154 IMP cell differentiation
GO:0030155 IMP regulation of cell adhesion
GO:0030198 IMP extracellular matrix organization
GO:0030238 IGI male sex determination
GO:0030279 IMP negative regulation of ossification
GO:0030502 IMP negative regulation of bone mineralization
GO:0030850 IEP prostate gland development
GO:0030857 IMP negative regulation of epithelial cell differentiation
GO:0030858 IMP positive regulation of epithelial cell differentiation
GO:0030879 IEP mammary gland development
GO:0030903 IEP notochord development
GO:0030916 IMP otic vesicle formation
GO:0031018 IMP endocrine pancreas development
GO:0032331 IMP negative regulation of chondrocyte differentiation
GO:0032332 IDA positive regulation of chondrocyte differentiation
GO:0034236 IEA protein kinase A catalytic subunit binding
GO:0035019 IMP somatic stem cell maintenance
GO:0035326 IDA enhancer binding
GO:0035622 IMP intrahepatic bile duct development
GO:0042127 IMP regulation of cell proliferation
GO:0043066 IMP negative regulation of apoptotic process
GO:0043234 ISS protein complex
GO:0043425 IEA bHLH transcription factor binding
GO:0043491 IMP protein kinase B signaling
GO:0043565 IDA sequence-specific DNA binding
GO:0044212 IDA transcription regulatory region DNA binding
GO:0044798 IDA nuclear transcription factor complex
GO:0045165 IGI cell fate commitment
GO:0045595 IMP regulation of cell differentiation
GO:0045662 IDA negative regulation of myoblast differentiation
GO:0045732 IDA positive regulation of protein catabolic process
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0046533 IGI negative regulation of photoreceptor cell differentiation
GO:0046982 IDA protein heterodimerization activity
GO:0048709 IMP oligodendrocyte differentiation
GO:0050679 IMP positive regulation of epithelial cell proliferation
GO:0050680 IMP negative regulation of epithelial cell proliferation
GO:0051216 IMP cartilage development
GO:0060008 IMP Sertoli cell differentiation
GO:0060009 IGI Sertoli cell development
GO:0060018 IGI astrocyte fate commitment
GO:0060041 IGI retina development in camera-type eye
GO:0060174 IEP limb bud formation
GO:0060221 IGI retinal rod cell differentiation
GO:0060350 IMP endochondral bone morphogenesis
GO:0060441 IGI epithelial tube branching involved in lung morphogenesis
GO:0060487 IMP lung epithelial cell differentiation
GO:0060512 IMP prostate gland morphogenesis
GO:0060517 IMP epithelial cell proliferation involved in prostatic bud elongation
GO:0060729 IMP intestinal epithelial structure maintenance
GO:0060784 IMP regulation of cell proliferation involved in tissue homeostasis
GO:0061036 IDA positive regulation of cartilage development
GO:0061046 IMP regulation of branching involved in lung morphogenesis
GO:0061138 IGI morphogenesis of a branching epithelium
GO:0070168 IMP negative regulation of biomineral tissue development
GO:0070371 IDA ERK1 and ERK2 cascade
GO:0071260 IDA cellular response to mechanical stimulus
GO:0071300 IDA cellular response to retinoic acid
GO:0071347 IEA cellular response to interleukin-1
GO:0071364 IDA cellular response to epidermal growth factor stimulus
GO:0071504 IDA cellular response to heparin
GO:0071560 IEP cellular response to transforming growth factor beta stimulus
GO:0071599 IEP otic vesicle development
GO:0072034 IMP renal vesicle induction
GO:0072170 IEP metanephric tubule development
GO:0072189 IGI ureter development
GO:0072190 IEP ureter urothelium development
GO:0072193 IMP ureter smooth muscle cell differentiation
GO:0072197 IGI ureter morphogenesis
GO:0072289 IGI metanephric nephron tubule formation
GO:0090090 IDA negative regulation of canonical Wnt signaling pathway
GO:0090103 IMP cochlea morphogenesis
GO:0090184 IGI positive regulation of kidney development
GO:0090190 IMP positive regulation of branching involved in ureteric bud morphogenesis
GO:0097157 IDA pre-mRNA intronic binding
GO:1901203 IMP positive regulation of extracellular matrix assembly
GO:2000020 ISS positive regulation of male gonad development
GO:2000138 IMP positive regulation of cell proliferation involved in heart morphogenesis
GO:2000741 ISS positive regulation of mesenchymal stem cell differentiation
GO:2000794 IMP regulation of epithelial cell proliferation involved in lung morphogenesis
GO:2001054 IMP negative regulation of mesenchymal cell apoptotic process

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSDART00000005676 sox9a-001 protein_coding Danio_rerio 0 603
ENSDART00000127937 sox9a-201 protein_coding Danio_rerio 0 547
ENSDART00000044224 sox7-201 protein_coding Danio_rerio 1e-18 100
ENSDART00000130271 sox7-001 protein_coding Danio_rerio 1e-18 100
ENST00000244745 SOX4-001 protein_coding Homo_sapiens 6e-27 128
ENST00000245479 SOX9-001 protein_coding Homo_sapiens 0 2290
ENST00000360880 SOX10-001 protein_coding Homo_sapiens 0 455
ENST00000396884 SOX10-002 protein_coding Homo_sapiens 0 455
ENST00000427770 SOX10-003 protein_coding Homo_sapiens 0 455
ENST00000446929 SOX10-004 protein_coding Homo_sapiens 0 209

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