ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Transcript Info
Description:
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000022060 Pdcd6-201 ENSMUSG00000021576 10090 - 13:74303121-74317326 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; C166Tie2+ ECmESENSMUST00000022060
Transcript ID C166 Tie2+ EC mES
ENSMUST00000022060 39.681±2.81 15.720±4.80 29.133±4.12

Conserved Regions

Not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001525 IEA angiogenesis
GO:0001938 ISS positive regulation of endothelial cell proliferation
GO:0004198 IBA calcium-dependent cysteine-type endopeptidase activity
GO:0005509 IMP calcium ion binding
GO:0005515 IPI protein binding
GO:0005634 ISS nucleus
GO:0005737 IDA cytoplasm
GO:0005768 IEA endosome
GO:0005783 IEA endoplasmic reticulum
GO:0006508 IBA proteolysis
GO:0006886 ISS intracellular protein transport
GO:0006915 IDA apoptotic process
GO:0006919 IDA activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0010595 ISS positive regulation of endothelial cell migration
GO:0016020 IEA membrane
GO:0030948 ISS negative regulation of vascular endothelial growth factor receptor signaling pathway
GO:0031410 IEA cytoplasmic vesicle
GO:0032007 ISS negative regulation of TOR signaling
GO:0034605 ISS cellular response to heat
GO:0036324 ISS vascular endothelial growth factor receptor-2 signaling pathway
GO:0042803 IPI protein homodimerization activity
GO:0045766 ISS positive regulation of angiogenesis
GO:0046983 IPI protein dimerization activity
GO:0048306 IPI calcium-dependent protein binding
GO:0051592 IDA response to calcium ion
GO:0051898 ISS negative regulation of protein kinase B signaling
GO:0060090 ISS binding, bridging
GO:0070062 IEA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000343123 RP11-43F13.1-006 processed_transcript Homo_sapiens 8.96831e-44 182
ENST00000502273 RP11-43F13.1-001 transcribed_unprocessed_pseudogene Homo_sapiens 0 222
ENST00000507290 RP11-43F13.1-004 processed_transcript Homo_sapiens 1.96182e-44 183
ENST00000507505 RP11-43F13.1-007 processed_transcript Homo_sapiens 0 226
ENST00000507841 RP11-43F13.1-003 processed_transcript Homo_sapiens 2.00386e-43 182
ENST00000512335 RP11-43F13.1-002 processed_transcript Homo_sapiens 5.04467e-44 183
ENST00000522848 RP11-43F13.1-008 processed_transcript Homo_sapiens 8.96831e-44 182

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