ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Transcript Info

Description:
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000064536 Adam17-001 ENSMUSG00000052593 10090 - 12:21323517-21373632 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; C166Tie2+ ECmESENSMUST00000064536
Transcript ID C166 Tie2+ EC mES
ENSMUST00000064536 25.210±4.84 16.578±3.27 8.145±1.75

Conserved Regions

Not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0002467 IMP germinal center formation
GO:0004222 TAS metalloendopeptidase activity
GO:0005112 ISS Notch binding
GO:0005515 IPI protein binding
GO:0005576 TAS extracellular region
GO:0005737 IDA cytoplasm
GO:0005886 TAS plasma membrane
GO:0006508 ISS proteolysis
GO:0006509 IMP membrane protein ectodomain proteolysis
GO:0007219 IEA Notch signaling pathway
GO:0007220 ISS Notch receptor processing
GO:0008237 IDA metallopeptidase activity
GO:0008270 IEA zinc ion binding
GO:0017124 IEA SH3 domain binding
GO:0030183 IMP B cell differentiation
GO:0030511 IMP positive regulation of transforming growth factor beta receptor signaling pathway
GO:0033025 IMP regulation of mast cell apoptotic process
GO:0033077 IMP T cell differentiation in thymus
GO:0042493 IMP response to drug
GO:0048536 IMP spleen development
GO:0048870 IMP cell motility
GO:0051088 IDA PMA-inducible membrane protein ectodomain proteolysis
GO:0051272 IMP positive regulation of cellular component movement

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSDART00000153339 adam17b-001 protein_coding Danio_rerio 4e-38 165
ENST00000310823 ADAM17-001 protein_coding Homo_sapiens 0 2953
ENST00000470914 IAH1-001 protein_coding Homo_sapiens 2.00386e-43 182
ENST00000478059 ADAM17-002 retained_intron Homo_sapiens 0 695
ENST00000484826 IAH1-014 retained_intron Homo_sapiens 0.00000002 64
ENST00000497134 ADAM17-003 protein_coding Homo_sapiens 0 942
ENST00000497473 IAH1-003 protein_coding Homo_sapiens 9.94922e-44 182
ENST00000618923 ADAM17-201 protein_coding Homo_sapiens 0 896

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