ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Transcript Info
Description:
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000079063 Sox11-001 ENSMUSG00000063632 10090 - 12:27334264-27342574 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; C166Tie2+ ECmESENSMUST00000079063
Transcript ID C166 Tie2+ EC mES
ENSMUST00000079063 0.846±0.18 4.876±7.28 7.465±3.02

Conserved Regions

Not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0000976 IDA transcription regulatory region sequence-specific DNA binding
GO:0000979 IEA RNA polymerase II core promoter sequence-specific DNA binding
GO:0001071 IDA nucleic acid binding transcription factor activity
GO:0001077 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0001105 IDA RNA polymerase II transcription coactivator activity
GO:0001158 IDA enhancer sequence-specific DNA binding
GO:0001501 IMP skeletal system development
GO:0001822 IEA kidney development
GO:0001841 IMP neural tube formation
GO:0002089 IMP lens morphogenesis in camera-type eye
GO:0003151 IMP outflow tract morphogenesis
GO:0003211 IMP cardiac ventricle formation
GO:0003357 IMP noradrenergic neuron differentiation
GO:0003700 IEA sequence-specific DNA binding transcription factor activity
GO:0003705 ISO RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity
GO:0005515 IEA protein binding
GO:0005634 IDA nucleus
GO:0005737 ISS cytoplasm
GO:0006366 ISO transcription from RNA polymerase II promoter
GO:0006412 IEA translation
GO:0008135 ISS translation factor activity, nucleic acid binding
GO:0008283 IEA cell proliferation
GO:0008284 IMP positive regulation of cell proliferation
GO:0010628 IMP positive regulation of gene expression
GO:0010629 IMP negative regulation of gene expression
GO:0014003 IEA oligodendrocyte development
GO:0014009 IMP glial cell proliferation
GO:0014032 IMP neural crest cell development
GO:0017015 IEA regulation of transforming growth factor beta receptor signaling pathway
GO:0021510 IMP spinal cord development
GO:0021782 IMP glial cell development
GO:0030182 IEA neuron differentiation
GO:0030513 IMP positive regulation of BMP signaling pathway
GO:0035332 IMP positive regulation of hippo signaling
GO:0035914 IMP skeletal muscle cell differentiation
GO:0045666 IDA positive regulation of neuron differentiation
GO:0045669 ISS positive regulation of osteoblast differentiation
GO:0045778 IMP positive regulation of ossification
GO:0045893 IMP positive regulation of transcription, DNA-templated
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0046887 IMP positive regulation of hormone secretion
GO:0048485 IMP sympathetic nervous system development
GO:0048557 IMP embryonic digestive tract morphogenesis
GO:0048704 IMP embryonic skeletal system morphogenesis
GO:0050672 IEA negative regulation of lymphocyte proliferation
GO:0050769 IDA positive regulation of neurogenesis
GO:0060022 IMP hard palate development
GO:0060023 IMP soft palate development
GO:0060174 IMP limb bud formation
GO:0060253 IMP negative regulation of glial cell proliferation
GO:0060412 IMP ventricular septum morphogenesis
GO:0060425 IMP lung morphogenesis
GO:0060548 IMP negative regulation of cell death
GO:0060563 IMP neuroepithelial cell differentiation
GO:0061029 IMP eyelid development in camera-type eye
GO:0061053 IMP somite development
GO:0061303 IMP cornea development in camera-type eye
GO:0061386 IMP closure of optic fissure
GO:0072395 IEA signal transduction involved in cell cycle checkpoint
GO:2000648 ISS positive regulation of stem cell proliferation
GO:2000678 ISS negative regulation of transcription regulatory region DNA binding
GO:2001111 IMP positive regulation of lens epithelial cell proliferation

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSDART00000100998 sox6-201 protein_coding Danio_rerio 0.000000000009 79
ENSDART00000149843 sox6-003 retained_intron Danio_rerio 0.000000000009 79
ENSDART00000150068 sox6-001 protein_coding Danio_rerio 0.000000000009 79
ENST00000244745 SOX4-001 protein_coding Homo_sapiens 0 305
ENST00000322002 SOX11-001 protein_coding Homo_sapiens 0 998
ENST00000330949 SOX1-001 protein_coding Homo_sapiens 0.00000002 66
ENST00000342665 SOX12-001 protein_coding Homo_sapiens 0 265
ENST00000376945 SOX21-001 protein_coding Homo_sapiens 0.00000000000002 86

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