ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Transcript Info
Description:
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000099151 Sox2-001 ENSMUSG00000074637 10090 + 3:34650405-34652461 protein_coding

Mus musculus Ensembl GRCm38

Genome
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Expression Patterns


Heat Map
Numeric Values
Transcript'; Tie2+ ECmESENSMUST00000099151
Transcript ID Tie2+ EC mES
ENSMUST00000099151 0.321±0.04 0.893±0.08

Conserved Regions

Not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 IGI negative regulation of transcription from RNA polymerase II promoter
GO:0000976 IEA transcription regulatory region sequence-specific DNA binding
GO:0000981 IDA sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0001077 IEA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0001649 IEA osteoblast differentiation
GO:0001654 IEA eye development
GO:0001708 IMP cell fate specification
GO:0001714 ISO endodermal cell fate specification
GO:0002052 IMP positive regulation of neuroblast proliferation
GO:0003677 IDA DNA binding
GO:0003682 IDA chromatin binding
GO:0003700 IDA sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005667 IDA transcription factor complex
GO:0005737 IDA cytoplasm
GO:0005829 IEA cytosol
GO:0006355 IDA regulation of transcription, DNA-templated
GO:0006357 IDA regulation of transcription from RNA polymerase II promoter
GO:0006366 IDA transcription from RNA polymerase II promoter
GO:0007050 IEA cell cycle arrest
GO:0007605 IMP sensory perception of sound
GO:0009611 IEA response to wounding
GO:0010033 IDA response to organic substance
GO:0010468 IEA regulation of gene expression
GO:0019827 IMP stem cell maintenance
GO:0021879 IMP forebrain neuron differentiation
GO:0021983 IEA pituitary gland development
GO:0021984 IMP adenohypophysis development
GO:0021987 IMP cerebral cortex development
GO:0022409 IEA positive regulation of cell-cell adhesion
GO:0030178 IGI negative regulation of Wnt signaling pathway
GO:0030539 IMP male genitalia development
GO:0030858 IDA positive regulation of epithelial cell differentiation
GO:0030900 IEA forebrain development
GO:0030910 IGI olfactory placode formation
GO:0032526 IDA response to retinoic acid
GO:0035019 IEA somatic stem cell maintenance
GO:0035198 IEA miRNA binding
GO:0042246 IEA tissue regeneration
GO:0042472 IMP inner ear morphogenesis
GO:0043281 IEA regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0043410 IEA positive regulation of MAPK cascade
GO:0043565 IDA sequence-specific DNA binding
GO:0043586 IMP tongue development
GO:0044212 IDA transcription regulatory region DNA binding
GO:0044798 IDA nuclear transcription factor complex
GO:0045165 IDA cell fate commitment
GO:0045596 IMP negative regulation of cell differentiation
GO:0045597 IEA positive regulation of cell differentiation
GO:0045665 IDA negative regulation of neuron differentiation
GO:0045666 IMP positive regulation of neuron differentiation
GO:0045668 IDA negative regulation of osteoblast differentiation
GO:0045747 IDA positive regulation of Notch signaling pathway
GO:0045893 IEA positive regulation of transcription, DNA-templated
GO:0045944 IGI positive regulation of transcription from RNA polymerase II promoter
GO:0046148 IMP pigment biosynthetic process
GO:0046982 IDA protein heterodimerization activity
GO:0048286 IDA lung alveolus development
GO:0048568 IMP embryonic organ development
GO:0048646 IMP anatomical structure formation involved in morphogenesis
GO:0048663 IMP neuron fate commitment
GO:0048839 IEA inner ear development
GO:0048852 IMP diencephalon morphogenesis
GO:0048863 IDA stem cell differentiation
GO:0050680 IEA negative regulation of epithelial cell proliferation
GO:0050767 IGI regulation of neurogenesis
GO:0050910 IMP detection of mechanical stimulus involved in sensory perception of sound
GO:0050973 IMP detection of mechanical stimulus involved in equilibrioception
GO:0060042 IMP retina morphogenesis in camera-type eye
GO:0060235 IGI lens induction in camera-type eye
GO:0060441 IDA epithelial tube branching involved in lung morphogenesis
GO:0070848 IEA response to growth factor
GO:0090090 IEA negative regulation of canonical Wnt signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSDART00000104493 sox2-001 protein_coding Danio_rerio 0 782
ENSDART00000058910 sox19b-001 protein_coding Danio_rerio 0 248
ENSDART00000075617 sox3-001 protein_coding Danio_rerio 0 244
ENSDART00000049339 sox21a-001 protein_coding Danio_rerio 4.00001e-40 171
ENST00000272193 SOX13-004 processed_transcript Homo_sapiens 0.00003 55
ENST00000306087 SOX14-001 protein_coding Homo_sapiens 0 270
ENST00000325404 SOX2-001 protein_coding Homo_sapiens 0 2990
ENST00000330949 SOX1-001 protein_coding Homo_sapiens 0 372
ENST00000367204 SOX13-002 protein_coding Homo_sapiens 0.00007 55
ENST00000370536 SOX3-001 protein_coding Homo_sapiens 0 316
ENST00000376945 SOX21-001 protein_coding Homo_sapiens 0 315
ENST00000517740 RP11-383J24.2-001 processed_pseudogene Homo_sapiens 0 333
ENST00000525258 SOX13-009 retained_intron Homo_sapiens 0.00005 53
ENST00000618875 SOX13-201 protein_coding Homo_sapiens 0.00006 55

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