ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Transcript Info
Description:
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000178477 Nkx2-1-001 ENSMUSG00000001496 10090 - 12:56531958-56535106 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; C166Tie2+ ECmESENSMUST00000178477
Transcript ID C166 Tie2+ EC mES
ENSMUST00000178477 0.022±0.00 0.056±0.04 0.055±0.03

Conserved Regions

Not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0001047 IDA core promoter binding
GO:0001764 IMP neuron migration
GO:0003700 IDA sequence-specific DNA binding transcription factor activity
GO:0003705 IDA RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005654 ISS nucleoplasm
GO:0005667 IDA transcription factor complex
GO:0006355 IDA regulation of transcription, DNA-templated
GO:0006357 IDA regulation of transcription from RNA polymerase II promoter
GO:0006366 IDA transcription from RNA polymerase II promoter
GO:0006644 IGI phospholipid metabolic process
GO:0007389 IGI pattern specification process
GO:0007411 IMP axon guidance
GO:0007420 IGI brain development
GO:0007492 IMP endoderm development
GO:0007626 IMP locomotory behavior
GO:0009887 IMP organ morphogenesis
GO:0021537 IMP telencephalon development
GO:0021759 IMP globus pallidus development
GO:0021766 IMP hippocampus development
GO:0021795 IMP cerebral cortex cell migration
GO:0021798 IMP forebrain dorsal/ventral pattern formation
GO:0021877 IGI forebrain neuron fate commitment
GO:0021879 IMP forebrain neuron differentiation
GO:0021892 IMP cerebral cortex GABAergic interneuron differentiation
GO:0021895 IGI cerebral cortex neuron differentiation
GO:0021983 IMP pituitary gland development
GO:0022029 IMP telencephalon cell migration
GO:0030324 IMP lung development
GO:0030878 IMP thyroid gland development
GO:0031128 IMP developmental induction
GO:0033327 IMP Leydig cell differentiation
GO:0042753 IMP positive regulation of circadian rhythm
GO:0043565 IDA sequence-specific DNA binding
GO:0044212 IDA transcription regulatory region DNA binding
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0045893 IGI positive regulation of transcription, DNA-templated
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0048511 IEA rhythmic process
GO:0048646 IMP anatomical structure formation involved in morphogenesis
GO:0048663 IMP neuron fate commitment
GO:0048709 IGI oligodendrocyte differentiation
GO:0060430 IGI lung saccule development
GO:0060486 IGI Clara cell differentiation
GO:0060510 IGI Type II pneumocyte differentiation

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSDART00000153363 hmx3b-001 protein_coding Danio_rerio 0.0001 53
ENST00000258829 NKX2-8-001 protein_coding Homo_sapiens 8e-35 152
ENST00000325017 NKX2-6-001 protein_coding Homo_sapiens 9e-33 145
ENST00000329198 NKX2-5-001 protein_coding Homo_sapiens 3e-35 154
ENST00000351817 NKX2-4-001 protein_coding Homo_sapiens 0 337
ENST00000354822 NKX2-1-002 protein_coding Homo_sapiens 0 1720
ENST00000357878 HMX3-001 protein_coding Homo_sapiens 0.000000003 68
ENST00000377142 NKX2-2-001 protein_coding Homo_sapiens 1.99965e-42 178
ENST00000424406 NKX2-5-003 protein_coding Homo_sapiens 2e-35 154
ENST00000498187 NKX2-1-001 protein_coding Homo_sapiens 0 1772
ENST00000518149 NKX2-1-004 protein_coding Homo_sapiens 0 1722
ENST00000521848 NKX2-5-004 protein_coding Homo_sapiens 2e-35 154
ENST00000522719 NKX2-1-003 protein_coding Homo_sapiens 0 1657

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