ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Transcript Info

Description: NK2 homeobox 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000522719 NKX2-1-003 ENSG00000136352 9606 - 14:36517217-36520134 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHUVECENST00000522719
Transcript ID BECs HAoEC HUVEC
ENST00000522719 0.031±0.00 0.048±0.02 0.035±0.00

Conserved Regions

Not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001047 ISS core promoter binding
GO:0003677 IMP:IEA DNA binding
GO:0003700 IDA sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005654 ISS nucleoplasm
GO:0007420 IMP brain development
GO:0009725 IEP response to hormone
GO:0010628 IDA positive regulation of gene expression
GO:0010719 IDA negative regulation of epithelial to mesenchymal transition
GO:0019899 IPI enzyme binding
GO:0021759 IMP globus pallidus development
GO:0030324 IEP lung development
GO:0030336 IDA negative regulation of cell migration
GO:0030512 IDA negative regulation of transforming growth factor beta receptor signaling pathway
GO:0030878 IMP thyroid gland development
GO:0030900 IEP forebrain development
GO:0042753 ISS positive regulation of circadian rhythm
GO:0044212 IDA transcription regulatory region DNA binding
GO:0045892 ISS negative regulation of transcription, DNA-templated
GO:0045893 ISS positive regulation of transcription, DNA-templated
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0048511 IEA rhythmic process
GO:0060441 IEP epithelial tube branching involved in lung morphogenesis

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000001536 Nkx2-1-002 protein_coding Mus_musculus 0 1657
ENSMUST00000178477 Nkx2-1-001 protein_coding Mus_musculus 0 1657
ENSMUST00000067020 Nkx2-4-001 protein_coding Mus_musculus 0 388
ENSMUST00000015723 Nkx2-5-001 protein_coding Mus_musculus 0 193
ENSDART00000022377 nkx2.5-001 protein_coding Danio_rerio 3e-29 134
ENSMUST00000072631 Nkx2-9-001 protein_coding Mus_musculus 1e-28 132
ENSDART00000005296 nkx2.9-001 protein_coding Danio_rerio 2e-16 92
ENSDART00000153363 hmx3b-001 protein_coding Danio_rerio 0.00000004 64

Loading