ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Transcript Info
Description: transcription factor AP-4 (activating enhancer binding protein 4)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000204517 TFAP4-001 ENSG00000090447 9606 - 16:4257186-4273075 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000204517
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000204517 2.972±0.00 1.218±0.87 1.142±0.00 1.377±0.00 1.477±0.92

Conserved Regions

Not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000978 IEA RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0001077 IEA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0003677 IDA DNA binding
GO:0003705 IDA RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0006366 IDA transcription from RNA polymerase II promoter
GO:0006461 IDA protein complex assembly
GO:0006978 IDA DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
GO:0008285 IMP negative regulation of cell proliferation
GO:0010629 IEA negative regulation of gene expression
GO:0017053 ISS transcriptional repressor complex
GO:0042803 IPI protein homodimerization activity
GO:0042826 IPI histone deacetylase binding
GO:0043065 IDA positive regulation of apoptotic process
GO:0043392 IDA negative regulation of DNA binding
GO:0043565 IDA sequence-specific DNA binding
GO:0043922 IDA negative regulation by host of viral transcription
GO:0043923 IDA positive regulation by host of viral transcription
GO:0044212 IDA transcription regulatory region DNA binding
GO:0045736 IDA negative regulation of cyclin-dependent protein serine/threonine kinase activity
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0045893 IMP positive regulation of transcription, DNA-templated
GO:0045944 IEA positive regulation of transcription from RNA polymerase II promoter
GO:0046983 IEA protein dimerization activity
GO:0070888 IDA E-box binding
GO:0071157 IMP negative regulation of cell cycle arrest
GO:0071549 IEA cellular response to dexamethasone stimulus
GO:2001269 IEA positive regulation of cysteine-type endopeptidase activity involved in apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000005862 Tfap4-201 protein_coding Mus_musculus 0 1986

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