ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Transcript Info
Description: serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000254722 SERPINF1-001 ENSG00000132386 9606 + 17:1761959-1777574 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHUVECENST00000254722
Transcript ID BECs HAoEC HUVEC
ENST00000254722 0.256±0.00 0.059±0.05 0.060±0.01

Conserved Regions

Not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001822 IEA kidney development
GO:0004867 IBA serine-type endopeptidase inhibitor activity
GO:0005576 IDA extracellular region
GO:0005604 IEA basement membrane
GO:0005615 IDA extracellular space
GO:0007275 TAS multicellular organismal development
GO:0007568 IEA aging
GO:0007614 IEA short-term memory
GO:0008283 TAS cell proliferation
GO:0010447 IEA response to acidity
GO:0010596 IEA negative regulation of endothelial cell migration
GO:0010629 IEA negative regulation of gene expression
GO:0010951 IBA negative regulation of endopeptidase activity
GO:0010976 IEA positive regulation of neuron projection development
GO:0016525 IDA negative regulation of angiogenesis
GO:0030162 IBA regulation of proteolysis
GO:0030424 IEA axon
GO:0031012 IDA extracellular matrix
GO:0042698 IEA ovulation cycle
GO:0043025 IEA neuronal cell body
GO:0043203 IEA axon hillock
GO:0046685 IEA response to arsenic-containing substance
GO:0048471 IEA perinuclear region of cytoplasm
GO:0050728 IEA negative regulation of inflammatory response
GO:0050769 IDA positive regulation of neurogenesis
GO:0060041 IEA retina development in camera-type eye
GO:0060770 IEA negative regulation of epithelial cell proliferation involved in prostate gland development
GO:0070062 IDA extracellular vesicular exosome
GO:0071279 IEA cellular response to cobalt ion
GO:0071300 IEA cellular response to retinoic acid
GO:0071333 IEA cellular response to glucose stimulus
GO:0071549 IEA cellular response to dexamethasone stimulus
GO:1901215 IEA negative regulation of neuron death

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000000769 Serpinf1-001 protein_coding Mus_musculus 0 1251
ENSMUST00000137103 Serpinf1-006 protein_coding Mus_musculus 0 573
ENSMUST00000125982 Serpinf1-005 protein_coding Mus_musculus 0 409
ENSMUST00000138661 Serpinf1-002 protein_coding Mus_musculus 0 270
ENSMUST00000155009 Serpinf1-003 protein_coding Mus_musculus 0 198
ENSMUST00000168902 Serpinf1-007 nonsense_mediated_decay Mus_musculus 6e-17 94

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