ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Transcript Info
Description: endothelial PAS domain protein 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000263734 EPAS1-001 ENSG00000116016 9606 + 2:46297402-46386703 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHMVEC-DHUVECENST00000263734
Transcript ID BECs HAoEC HMVEC-D HUVEC
ENST00000263734 8.567±0.12 159.189±115.37 154.351±0.00 81.253±58.51

Conserved Regions

Not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001077 IEA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0001525 IEA angiogenesis
GO:0001666 IDA response to hypoxia
GO:0001892 IEA embryonic placenta development
GO:0001974 IEA blood vessel remodeling
GO:0002027 IEA regulation of heart rate
GO:0003677 IGI DNA binding
GO:0003700 IEA sequence-specific DNA binding transcription factor activity
GO:0004871 IEA signal transducer activity
GO:0005515 IPI:IEA protein binding
GO:0005634 IEA nucleus
GO:0005654 TAS nucleoplasm
GO:0005667 IDA transcription factor complex
GO:0005737 IEA cytoplasm
GO:0005829 TAS cytosol
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006366 TAS transcription from RNA polymerase II promoter
GO:0006979 IEA response to oxidative stress
GO:0007005 IEA mitochondrion organization
GO:0007165 IEA signal transduction
GO:0007601 IEA visual perception
GO:0008134 IPI transcription factor binding
GO:0030097 IEA hemopoiesis
GO:0030154 IEA cell differentiation
GO:0030218 IEA erythrocyte differentiation
GO:0030324 IEA lung development
GO:0035035 IPI histone acetyltransferase binding
GO:0042415 IEA norepinephrine metabolic process
GO:0043129 IEA surfactant homeostasis
GO:0043565 IDA sequence-specific DNA binding
GO:0043619 IEA regulation of transcription from RNA polymerase II promoter in response to oxidative stress
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0046982 IPI protein heterodimerization activity
GO:0046983 IEA protein dimerization activity
GO:0048469 IEA cell maturation
GO:0048625 ISS myoblast fate commitment
GO:0055072 IEA iron ion homeostasis
GO:0061418 TAS regulation of transcription from RNA polymerase II promoter in response to hypoxia
GO:0071456 IDA cellular response to hypoxia

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000024954 Epas1-201 protein_coding Mus_musculus 0 2972

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