| Transcript ID | BECs | HAoEC | HHSEC | HMVEC-D | HUVEC |
|---|---|---|---|---|---|
| ENST00000288368 | 1.306±0.47 | 3.708±7.11 | 11.169±0.00 | 1.255±0.00 | 7.405±5.00 |
ANGIOGENES: A knowledge database for angiogenesis
Institute of Cardiovascular Regeneration, Goethe University Frankfurt
Transcript Info |
||||||
| Description: | phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2 | |||||
|---|---|---|---|---|---|---|
| Transcript Accession | Transcript Name | Contained in Gene | Tax ID | Strand | Position | Biotype |
ENST00000288368  |
PREX2-001 |
ENSG00000046889 |
9606 | + |
8:67952118-68237030  |
protein_coding |
Expression Patterns
|
Conserved Regions |
|---|
| Not located within a conserved region. |
Gene Ontology | ||
|---|---|---|
| GO ID | Evidence Type | GO Description |
| GO:0005089 | IEA | Rho guanyl-nucleotide exchange factor activity |
| GO:0005515 | IEA | protein binding |
| GO:0005886 | IEA | plasma membrane |
| GO:0007186 | IDA | G-protein coupled receptor signaling pathway |
| GO:0008344 | IEA | adult locomotory behavior |
| GO:0014065 | IEA | phosphatidylinositol 3-kinase signaling |
| GO:0030675 | IDA | Rac GTPase activator activity |
| GO:0030676 | IDA | Rac guanyl-nucleotide exchange factor activity |
| GO:0032855 | IDA | positive regulation of Rac GTPase activity |
| GO:0035023 | IEA | regulation of Rho protein signal transduction |
| GO:0035556 | IEA | intracellular signal transduction |
| GO:0048813 | IEA | dendrite morphogenesis |
Homologs | |||||
| ENSEMBL Accession | Gene Name | Biotype | Species | E-Value | Bit Score |
|
ENSMUST00000027056
|
Prex2-001 | protein_coding | Mus_musculus | 0 | 5384 |
|
ENSMUST00000189822
|
Prex2-003 | retained_intron | Mus_musculus | 0 | 1565 |
|
ENSMUST00000187694
|
Prex2-004 | retained_intron | Mus_musculus | 0 | 747 |
|
ENSMUST00000190935
|
Prex2-002 | retained_intron | Mus_musculus | 5e-35 | 156 |
