ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Transcript Info
Description: hypoxia inducible factor 1, alpha subunit inhibitor
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000299163 HIF1AN-002 ENSG00000166135 9606 + 10:100535859-100559998 protein_coding

Homo sapiens Ensembl GRCh38

Genome
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Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHMVEC-DHUVECENST00000299163
Transcript ID BECs HAoEC HMVEC-D HUVEC
ENST00000299163 3.462±0.00 6.582±3.32 4.478±0.00 4.339±1.85

Conserved Regions

Not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005112 IPI Notch binding
GO:0005506 IDA iron ion binding
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005829 TAS cytosol
GO:0006351 IEA transcription, DNA-templated
GO:0008270 IDA zinc ion binding
GO:0016706 EXP oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors
GO:0019826 NAS oxygen sensor activity
GO:0031406 IDA carboxylic acid binding
GO:0036138 IDA peptidyl-histidine hydroxylation
GO:0036139 IDA peptidyl-histidine dioxygenase activity
GO:0036140 IDA peptidyl-asparagine 3-dioxygenase activity
GO:0042264 IDA peptidyl-aspartic acid hydroxylation
GO:0042265 IDA peptidyl-asparagine hydroxylation
GO:0042803 IDA protein homodimerization activity
GO:0045663 IDA positive regulation of myoblast differentiation
GO:0045746 IDA negative regulation of Notch signaling pathway
GO:0048037 IDA cofactor binding
GO:0048471 IDA perinuclear region of cytoplasm
GO:0051059 IPI NF-kappaB binding
GO:0055114 IDA oxidation-reduction process
GO:0061418 TAS regulation of transcription from RNA polymerase II promoter in response to hypoxia
GO:0061428 IDA negative regulation of transcription from RNA polymerase II promoter in response to hypoxia
GO:0071456 TAS cellular response to hypoxia
GO:0071532 IPI ankyrin repeat binding
GO:2001214 NAS positive regulation of vasculogenesis

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000040455 Hif1an-001 protein_coding Mus_musculus 0 1908
ENSMUST00000074912 2010012O05Rik-201 protein_coding Mus_musculus 0.000001 62

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