Transcript ID | HAoEC | HMVEC-D | HUVEC |
---|---|---|---|
ENST00000302850 | 0.701±0.36 | 0.518±0.00 | 0.751±0.24 |
Genome
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Transcript Info |
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Description: | insulin receptor | |||||
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Transcript Accession | Transcript Name | Contained in Gene | Tax ID | Strand | Position | Biotype |
ENST00000302850 ![]() |
INSR-001 |
ENSG00000171105 ![]() |
9606 | - |
19:7116627-7294034 |
protein_coding |
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Expression Patterns
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Conserved Regions |
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Not located within a conserved region. |
Gene Ontology | ||
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GO ID | Evidence Type | GO Description |
GO:0000187 | IMP | activation of MAPK activity |
GO:0001934 | IDA | positive regulation of protein phosphorylation |
GO:0003007 | IMP | heart morphogenesis |
GO:0004672 | IEA | protein kinase activity |
GO:0004713 | IMP:IEA | protein tyrosine kinase activity |
GO:0004714 | IEA | transmembrane receptor protein tyrosine kinase activity |
GO:0004716 | IDA | receptor signaling protein tyrosine kinase activity |
GO:0005009 | IDA | insulin-activated receptor activity |
GO:0005159 | IDA | insulin-like growth factor receptor binding |
GO:0005515 | IPI:IEA | protein binding |
GO:0005524 | IDA:IEA | ATP binding |
GO:0005525 | IDA | GTP binding |
GO:0005886 | IC | plasma membrane |
GO:0005887 | IDA | integral component of plasma membrane |
GO:0005899 | IMP | insulin receptor complex |
GO:0005901 | IDA | caveola |
GO:0005975 | IEA | carbohydrate metabolic process |
GO:0006355 | IMP | regulation of transcription, DNA-templated |
GO:0006468 | IEA | protein phosphorylation |
GO:0007169 | IEA | transmembrane receptor protein tyrosine kinase signaling pathway |
GO:0007186 | IDA | G-protein coupled receptor signaling pathway |
GO:0008284 | IC | positive regulation of cell proliferation |
GO:0008286 | IDA | insulin receptor signaling pathway |
GO:0008544 | IEA | epidermis development |
GO:0009887 | IEA | organ morphogenesis |
GO:0010008 | TAS | endosome membrane |
GO:0016020 | IDA:IEA | membrane |
GO:0016021 | IEA | integral component of membrane |
GO:0016772 | IEA | transferase activity, transferring phosphorus-containing groups |
GO:0018108 | IDA | peptidyl-tyrosine phosphorylation |
GO:0019087 | IMP | transformation of host cell by virus |
GO:0023014 | IDA | signal transduction by phosphorylation |
GO:0030238 | IEA | male sex determination |
GO:0030335 | IMP | positive regulation of cell migration |
GO:0031017 | IEA | exocrine pancreas development |
GO:0031994 | IPI | insulin-like growth factor I binding |
GO:0031995 | IPI | insulin-like growth factor II binding |
GO:0032147 | IMP | activation of protein kinase activity |
GO:0032148 | IDA | activation of protein kinase B activity |
GO:0032869 | IDA | cellular response to insulin stimulus |
GO:0038083 | IEA | peptidyl-tyrosine autophosphorylation |
GO:0042593 | IMP | glucose homeostasis |
GO:0043235 | IDA | receptor complex |
GO:0043410 | IMP | positive regulation of MAPK cascade |
GO:0043548 | IPI:IEA | phosphatidylinositol 3-kinase binding |
GO:0043559 | IDA | insulin binding |
GO:0043560 | IPI:IEA | insulin receptor substrate binding |
GO:0045429 | IMP | positive regulation of nitric oxide biosynthetic process |
GO:0045725 | IDA | positive regulation of glycogen biosynthetic process |
GO:0045740 | IMP | positive regulation of DNA replication |
GO:0045821 | IMP | positive regulation of glycolytic process |
GO:0045840 | IMP | positive regulation of mitosis |
GO:0045995 | IMP | regulation of embryonic development |
GO:0046326 | NAS | positive regulation of glucose import |
GO:0046777 | IDA:IEA | protein autophosphorylation |
GO:0048639 | IMP | positive regulation of developmental growth |
GO:0051290 | IDA | protein heterotetramerization |
GO:0051425 | IPI | PTB domain binding |
GO:0051897 | IMP | positive regulation of protein kinase B signaling |
GO:0060267 | IDA | positive regulation of respiratory burst |
GO:0070062 | IDA | extracellular vesicular exosome |
GO:0071363 | IEA | cellular response to growth factor stimulus |
Homologs | |||||
ENSEMBL Accession | Gene Name | Biotype | Species | E-Value | Bit Score |
ENSMUST00000091291
![]() |
Insr-001 | protein_coding | Mus_musculus | 0 | 2555 |
ENSMUST00000139504
![]() |
Insr-002 | retained_intron | Mus_musculus | 0 | 1070 |