ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Transcript Info
Description: axin 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000307078 AXIN2-001 ENSG00000168646 9606 - 17:65528563-65561647 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; HAoECHUVECENST00000307078
Transcript ID HAoEC HUVEC
ENST00000307078 0.500±0.27 0.463±0.35

Conserved Regions

Not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001756 IEA somitogenesis
GO:0001934 IMP positive regulation of protein phosphorylation
GO:0001957 IBA intramembranous ossification
GO:0003139 IEA secondary heart field specification
GO:0003413 IEA chondrocyte differentiation involved in endochondral bone morphogenesis
GO:0005096 IBA GTPase activator activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005813 IDA centrosome
GO:0005881 IBA cytoplasmic microtubule
GO:0005886 IBA plasma membrane
GO:0005938 IBA cell cortex
GO:0008013 IBA beta-catenin binding
GO:0008277 IEA regulation of G-protein coupled receptor protein signaling pathway
GO:0008283 IEA cell proliferation
GO:0008285 IMP negative regulation of cell proliferation
GO:0009950 IBA dorsal/ventral axis specification
GO:0010718 IMP positive regulation of epithelial to mesenchymal transition
GO:0010942 IMP positive regulation of cell death
GO:0014069 IBA postsynaptic density
GO:0016023 IBA cytoplasmic membrane-bounded vesicle
GO:0019899 IPI enzyme binding
GO:0019901 IBA protein kinase binding
GO:0030111 IEA regulation of Wnt signaling pathway
GO:0030282 IEA bone mineralization
GO:0030877 NAS beta-catenin destruction complex
GO:0031625 IPI ubiquitin protein ligase binding
GO:0032423 IMP regulation of mismatch repair
GO:0034613 IDA cellular protein localization
GO:0035414 IMP negative regulation of catenin import into nucleus
GO:0038032 IEA termination of G-protein coupled receptor signaling pathway
GO:0042476 IMP odontogenesis
GO:0043547 IBA positive regulation of GTPase activity
GO:0043570 IMP maintenance of DNA repeat elements
GO:0045668 IBA negative regulation of osteoblast differentiation
GO:0048255 IMP mRNA stabilization
GO:0061181 IEA regulation of chondrocyte development
GO:0070016 IBA armadillo repeat domain binding
GO:0070411 IEA I-SMAD binding
GO:0070602 IMP regulation of centromeric sister chromatid cohesion
GO:0071407 IBA cellular response to organic cyclic compound
GO:0090090 IMP negative regulation of canonical Wnt signaling pathway
GO:0090244 IBA Wnt signaling pathway involved in somitogenesis

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000052915 Axin2-001 protein_coding Mus_musculus 0 3103
ENSMUST00000106711 Axin2-002 protein_coding Mus_musculus 0 1799
ENSMUST00000139682 Axin2-003 processed_transcript Mus_musculus 0 963
ENSMUST00000144130 Axin2-007 processed_transcript Mus_musculus 0 507
ENSMUST00000152909 Axin2-006 protein_coding Mus_musculus 0 346
ENSMUST00000140821 Axin2-005 protein_coding Mus_musculus 0 318
ENSMUST00000144511 Axin2-004 protein_coding Mus_musculus 0 230

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