ANGIOGENES

Transcript Accession	Transcript Name	Contained in Gene	Tax ID	Strand	Position	Biotype
Transcript Info
Description:	ring finger and FYVE-like domain containing E3 ubiquitin protein ligase
ENST00000315249	RFFL-001	ENSG00000092871	9606	-	17:35005990-35089319	protein_coding

Transcript ID	HAoEC	HUVEC
ENST00000315249	1.673±0.54	2.624±1.14

Conserved Regions
Not located within a conserved region.

Gene Ontology
GO ID	Evidence Type	GO Description
GO:0002020	IPI	protease binding
GO:0002039	IPI	p53 binding
GO:0002947	IDA	tumor necrosis factor receptor superfamily complex
GO:0005515	IPI:IEA	protein binding
GO:0005737	IDA	cytoplasm
GO:0005886	IDA	plasma membrane
GO:0006511	IDA	ubiquitin-dependent protein catabolic process
GO:0006886	IEA	intracellular protein transport
GO:0008270	IEA	zinc ion binding
GO:0010008	IDA	endosome membrane
GO:0010762	ISS	regulation of fibroblast migration
GO:0010804	IMP	negative regulation of tumor necrosis factor-mediated signaling pathway
GO:0016020	IDA	membrane
GO:0016023	IEA	cytoplasmic membrane-bounded vesicle
GO:0016874	IEA	ligase activity
GO:0019901	IPI	protein kinase binding
GO:0031625	IPI	ubiquitin protein ligase binding
GO:0032006	IC	regulation of TOR signaling
GO:0042787	IMP	protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0043161	IMP	proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0061630	IDA	ubiquitin protein ligase activity
GO:0070936	IDA	protein K48-linked ubiquitination
GO:1901797	IMP	negative regulation of signal transduction by p53 class mediator
GO:1902042	IMP	negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
GO:2001271	IMP	negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis

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