ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Transcript Info
Description: megakaryoblastic leukemia (translocation) 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000355630 MKL1-001 ENSG00000196588 9606 - 22:40410281-40636685 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; HAoECHMVEC-DHUVECENST00000355630
Transcript ID HAoEC HMVEC-D HUVEC
ENST00000355630 16.212±3.11 10.632±0.00 15.049±3.53

Conserved Regions

Not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000976 IEA transcription regulatory region sequence-specific DNA binding
GO:0003700 IEA sequence-specific DNA binding transcription factor activity
GO:0003713 ISS transcription coactivator activity
GO:0003779 IDA actin binding
GO:0003785 ISS actin monomer binding
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0006351 IEA transcription, DNA-templated
GO:0006357 IEA regulation of transcription from RNA polymerase II promoter
GO:0010735 IDA positive regulation of transcription via serum response element binding
GO:0043154 IEA negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0043522 IPI leucine zipper domain binding
GO:0045893 IEA positive regulation of transcription, DNA-templated
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0051145 IMP smooth muscle cell differentiation
GO:2001234 IEA negative regulation of apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000134469 Mkl1-004 protein_coding Mus_musculus 0 3217
ENSMUST00000149582 Mkl1-001 protein_coding Mus_musculus 0 3164
ENSMUST00000109579 Mkl1-002 protein_coding Mus_musculus 0 2795
ENSMUST00000135047 Mkl1-003 protein_coding Mus_musculus 0 2113
ENSMUST00000131235 Mkl1-005 protein_coding Mus_musculus 0 1971
ENSMUST00000123243 Mkl1-007 retained_intron Mus_musculus 0 547
ENSMUST00000147921 Mkl1-006 retained_intron Mus_musculus 0 472
ENSMUST00000145779 Mkl1-009 retained_intron Mus_musculus 0 267
ENSMUST00000009713 Mkl2-003 protein_coding Mus_musculus 0 261
ENSMUST00000149359 Mkl2-001 protein_coding Mus_musculus 0 255
ENSMUST00000154797 Mkl1-008 retained_intron Mus_musculus 0 200

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