ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Transcript Info
Description: calcium channel, voltage-dependent, P/Q type, alpha 1A subunit
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000360228 CACNA1A-001 ENSG00000141837 9606 - 19:13206442-13506224 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; HAoECHUVECENST00000360228
Transcript ID HAoEC HUVEC
ENST00000360228 0.044±0.03 0.013±0.01

Conserved Regions

Not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000096 IEA sulfur amino acid metabolic process
GO:0005216 IEA ion channel activity
GO:0005245 ISS voltage-gated calcium channel activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005886 IDA plasma membrane
GO:0005891 IEA voltage-gated calcium channel complex
GO:0006006 IEA glucose metabolic process
GO:0006112 TAS energy reserve metabolic process
GO:0006811 IEA ion transport
GO:0006816 IEA calcium ion transport
GO:0007204 ISS positive regulation of cytosolic calcium ion concentration
GO:0007214 IEA gamma-aminobutyric acid signaling pathway
GO:0007268 IBA synaptic transmission
GO:0007270 IEA neuron-neuron synaptic transmission
GO:0007274 IEA neuromuscular synaptic transmission
GO:0007416 IEA synapse assembly
GO:0007628 IEA adult walking behavior
GO:0008219 IDA cell death
GO:0008331 IBA high voltage-gated calcium channel activity
GO:0014051 IEA gamma-aminobutyric acid secretion
GO:0014056 IEA regulation of acetylcholine secretion, neurotransmission
GO:0016020 IEA membrane
GO:0016021 NAS integral component of membrane
GO:0016049 IEA cell growth
GO:0017156 IEA calcium ion-dependent exocytosis
GO:0017158 IEA regulation of calcium ion-dependent exocytosis
GO:0019226 IEA transmission of nerve impulse
GO:0019905 IDA syntaxin binding
GO:0021522 IEA spinal cord motor neuron differentiation
GO:0021590 IEA cerebellum maturation
GO:0021679 IEA cerebellar molecular layer development
GO:0021680 IEA cerebellar Purkinje cell layer development
GO:0021702 IEA cerebellar Purkinje cell differentiation
GO:0021750 IEA vestibular nucleus development
GO:0021953 IEA central nervous system neuron differentiation
GO:0030425 IEA dendrite
GO:0030644 IEA cellular chloride ion homeostasis
GO:0032353 IEA negative regulation of hormone biosynthetic process
GO:0034765 IEA regulation of ion transmembrane transport
GO:0035249 IEA synaptic transmission, glutamatergic
GO:0042133 IEA neurotransmitter metabolic process
GO:0042391 IEA regulation of membrane potential
GO:0042445 IEA hormone metabolic process
GO:0042995 IDA cell projection
GO:0043025 IEA neuronal cell body
GO:0043113 IEA receptor clustering
GO:0043524 IEA negative regulation of neuron apoptotic process
GO:0044281 TAS small molecule metabolic process
GO:0046872 IEA metal ion binding
GO:0048265 IEA response to pain
GO:0048266 IEA behavioral response to pain
GO:0048791 IEA calcium ion-dependent exocytosis of neurotransmitter
GO:0048813 IEA dendrite morphogenesis
GO:0050770 IEA regulation of axonogenesis
GO:0050796 TAS regulation of insulin secretion
GO:0050877 IEA neurological system process
GO:0050883 IEA musculoskeletal movement, spinal reflex action
GO:0050885 IEA neuromuscular process controlling balance
GO:0050905 IEA neuromuscular process
GO:0051899 TAS membrane depolarization
GO:0055085 IEA transmembrane transport
GO:0060024 IEA rhythmic synaptic transmission
GO:0070509 IBA calcium ion import
GO:0070588 IEA calcium ion transmembrane transport
GO:0086010 IBA membrane depolarization during action potential

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000122053 Cacna1a-002 protein_coding Mus_musculus 0 4564
ENSMUST00000121390 Cacna1a-001 protein_coding Mus_musculus 0 4564
ENSDART00000150130 cacna1ab-202 protein_coding Danio_rerio 0 1325
ENSDART00000138765 cacna1aa-002 protein_coding Danio_rerio 0 1293
ENSDART00000144774 cacna1aa-001 protein_coding Danio_rerio 0 1293
ENSDART00000013228 cacna1aa-201 protein_coding Danio_rerio 0 1288
ENSDART00000008139 cacna1ab-201 protein_coding Danio_rerio 0 1260
ENSMUST00000135382 Cacna1a-003 retained_intron Mus_musculus 0 1077
ENSMUST00000041342 Cacna1b-002 protein_coding Mus_musculus 0 1029
ENSMUST00000102939 Cacna1b-004 protein_coding Mus_musculus 0 1029
ENSMUST00000100348 Cacna1b-201 protein_coding Mus_musculus 0 1027
ENSMUST00000114447 Cacna1b-003 protein_coding Mus_musculus 0 1027
ENSMUST00000004214 Cacna1e-201 protein_coding Mus_musculus 0 1026
ENSMUST00000187541 Cacna1e-001 protein_coding Mus_musculus 0 1020
ENSMUST00000070864 Cacna1b-001 protein_coding Mus_musculus 0 1016
ENSMUST00000129620 Cacna1a-004 processed_transcript Mus_musculus 0 887
ENSMUST00000144879 Cacna1a-005 retained_intron Mus_musculus 0 832
ENSMUST00000153691 Cacna1a-010 processed_transcript Mus_musculus 0 704
ENSMUST00000141981 Cacna1a-008 retained_intron Mus_musculus 0 669
ENSDART00000134656 cacna1eb-001 protein_coding Danio_rerio 0 645
ENSMUST00000143215 Cacna1a-007 retained_intron Mus_musculus 0 505
ENSMUST00000126302 Cacna1a-006 retained_intron Mus_musculus 0 473
ENSDART00000149273 cacna1ab-003 processed_transcript Danio_rerio 0 416
ENSDART00000148949 cacna1ab-004 protein_coding Danio_rerio 0 207
ENSMUST00000125876 Tulp1-006 retained_intron Mus_musculus 0.00004 57
ENSMUST00000114794 Tulp1-004 protein_coding Mus_musculus 0.00004 57
ENSMUST00000140250 Tulp1-002 retained_intron Mus_musculus 0.00004 57
ENSMUST00000041819 Tulp1-001 protein_coding Mus_musculus 0.00004 57
ENSMUST00000130507 Cacna1a-009 processed_transcript Mus_musculus 2e-34 148

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