ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Transcript Info
Description: IQ motif containing GTPase activating protein 3
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000361170 IQGAP3-001 ENSG00000183856 9606 - 1:156525405-156572540 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHMVEC-DHUVECENST00000361170
Transcript ID BECs HAoEC HMVEC-D HUVEC
ENST00000361170 0.973±0.55 5.389±2.78 3.419±0.00 8.713±11.80

Conserved Regions

Not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000082 IEA G1/S transition of mitotic cell cycle
GO:0000187 IEA activation of MAPK activity
GO:0001934 IEA positive regulation of protein phosphorylation
GO:0005099 IEA Ras GTPase activator activity
GO:0005515 IEA protein binding
GO:0005516 IPI calmodulin binding
GO:0005622 IEA intracellular
GO:0005737 IEA cytoplasm
GO:0005911 IEA cell-cell junction
GO:0007165 IEA signal transduction
GO:0007264 IEA small GTPase mediated signal transduction
GO:0007265 IEA Ras protein signal transduction
GO:0008361 IEA regulation of cell size
GO:0010628 IEA positive regulation of gene expression
GO:0010629 IEA negative regulation of gene expression
GO:0016328 IEA lateral plasma membrane
GO:0017016 IEA Ras GTPase binding
GO:0017048 IEA Rho GTPase binding
GO:0032318 IEA regulation of Ras GTPase activity
GO:0032320 IEA positive regulation of Ras GTPase activity
GO:0033601 IEA positive regulation of mammary gland epithelial cell proliferation
GO:0070371 IEA ERK1 and ERK2 cascade
GO:0070856 IPI myosin VI light chain binding
GO:0071310 IEA cellular response to organic substance

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000071812 Iqgap3-001 protein_coding Mus_musculus 0 5059
ENSMUST00000194440 Iqgap3-005 protein_coding Mus_musculus 0 2379
ENSMUST00000195465 Iqgap3-002 nonsense_mediated_decay Mus_musculus 0 1905
ENSMUST00000167377 Iqgap1-201 protein_coding Mus_musculus 0 355
ENSDART00000110283 iqgap1-201 protein_coding Danio_rerio 0 294
ENSMUST00000194772 Iqgap3-006 retained_intron Mus_musculus 0 195

Loading