ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Transcript Info
Description: ADAM metallopeptidase domain 15
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000368413 ADAM15-002 ENSG00000143537 9606 + 1:155051316-155062769 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECENST00000368413
Transcript ID BECs HAoEC
ENST00000368413 172.772±49.29 55.922±11.78

Conserved Regions

Not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001525 IEA angiogenesis
GO:0001953 IMP negative regulation of cell-matrix adhesion
GO:0004222 IEA metalloendopeptidase activity
GO:0005178 IMP integrin binding
GO:0005515 IPI:IEA protein binding
GO:0005886 TAS plasma membrane
GO:0006508 IEA proteolysis
GO:0007160 TAS cell-matrix adhesion
GO:0007229 IMP integrin-mediated signaling pathway
GO:0008237 IDA metallopeptidase activity
GO:0008270 IEA zinc ion binding
GO:0009986 IDA cell surface
GO:0016021 IEA integral component of membrane
GO:0017124 IPI SH3 domain binding
GO:0022617 TAS extracellular matrix disassembly
GO:0030054 IEA cell junction
GO:0030198 TAS extracellular matrix organization
GO:0030308 IMP negative regulation of cell growth
GO:0030336 IMP negative regulation of cell migration
GO:0030574 IEA collagen catabolic process
GO:0031410 IEA cytoplasmic vesicle
GO:0042995 IEA cell projection
GO:0045087 IDA innate immune response
GO:0070062 IDA extracellular vesicular exosome
GO:0070528 IDA protein kinase C signaling
GO:1900121 IMP negative regulation of receptor binding

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000074582 Adam15-002 protein_coding Mus_musculus 0 1264
ENSMUST00000029676 Adam15-001 protein_coding Mus_musculus 0 1098
ENSMUST00000107448 Adam15-004 protein_coding Mus_musculus 0 1098
ENSMUST00000184651 Adam15-005 nonsense_mediated_decay Mus_musculus 0 1098
ENSMUST00000144608 Adam15-009 retained_intron Mus_musculus 0 667
ENSMUST00000134839 Adam15-006 retained_intron Mus_musculus 0 196
ENSMUST00000107446 Adam15-003 protein_coding Mus_musculus 3e-26 124

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