ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Transcript Info
Description: serine/threonine kinase 4
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000372806 STK4-003 ENSG00000101109 9606 + 20:44966474-45079959 protein_coding

Homo sapiens Ensembl GRCh38

Genome
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Expression Patterns


Heat Map
Numeric Values
Transcript'; HAoECHMVEC-DHUVECENST00000372806
Transcript ID HAoEC HMVEC-D HUVEC
ENST00000372806 4.570±2.01 5.593±0.00 4.956±3.28

Conserved Regions

Not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000287 IDA magnesium ion binding
GO:0000902 IDA cell morphogenesis
GO:0001569 IEA patterning of blood vessels
GO:0001841 IEA neural tube formation
GO:0003157 IEA endocardium development
GO:0004672 IEA protein kinase activity
GO:0004674 IDA:IEA protein serine/threonine kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005515 IPI protein binding
GO:0005524 IDA:IEA ATP binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005829 TAS cytosol
GO:0006468 IDA:IEA protein phosphorylation
GO:0006915 IDA apoptotic process
GO:0007165 TAS:IEA signal transduction
GO:0007417 IEA central nervous system development
GO:0008134 IPI transcription factor binding
GO:0008285 IEA negative regulation of cell proliferation
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0018105 IDA peptidyl-serine phosphorylation
GO:0030216 IEA keratinocyte differentiation
GO:0035329 TAS hippo signaling
GO:0035556 IDA intracellular signal transduction
GO:0042802 IPI identical protein binding
GO:0042803 IDA protein homodimerization activity
GO:0043065 IDA positive regulation of apoptotic process
GO:0043539 TAS protein serine/threonine kinase activator activity
GO:0046621 IEA negative regulation of organ growth
GO:0046777 IDA protein autophosphorylation
GO:0046983 IDA protein dimerization activity
GO:0060215 IEA primitive hemopoiesis
GO:0060706 IEA cell differentiation involved in embryonic placenta development
GO:0071902 TAS positive regulation of protein serine/threonine kinase activity
GO:0090090 IMP negative regulation of canonical Wnt signaling pathway
GO:0097284 IEA hepatocyte apoptotic process
GO:1902043 IEA positive regulation of extrinsic apoptotic signaling pathway via death domain receptors

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000018353 Stk4-001 protein_coding Mus_musculus 0 2540
ENSMUST00000088291 Stk4-003 protein_coding Mus_musculus 0 917
ENSMUST00000153319 Stk4-005 processed_transcript Mus_musculus 0 726
ENSMUST00000137866 Stk4-002 protein_coding Mus_musculus 0 601
ENSMUST00000134078 Stk4-004 protein_coding Mus_musculus 0 414

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