ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Transcript Info
Description: EPH receptor B2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000374632 EPHB2-002 ENSG00000133216 9606 + 1:22710970-22914270 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHMVEC-DHUVECENST00000374632
Transcript ID BECs HAoEC HMVEC-D HUVEC
ENST00000374632 4.199±0.00 5.113±1.59 7.489±0.00 8.763±5.82

Conserved Regions

Not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000902 IEA cell morphogenesis
GO:0001525 ISS angiogenesis
GO:0001655 ISS urogenital system development
GO:0004672 IEA protein kinase activity
GO:0004713 ISS:IEA protein tyrosine kinase activity
GO:0004872 IEA receptor activity
GO:0005003 IEA ephrin receptor activity
GO:0005005 ISS transmembrane-ephrin receptor activity
GO:0005102 IEA receptor binding
GO:0005515 IPI:IEA protein binding
GO:0005524 IEA ATP binding
GO:0005887 ISS:IEA integral component of plasma membrane
GO:0006468 IEA protein phosphorylation
GO:0007169 IEA transmembrane receptor protein tyrosine kinase signaling pathway
GO:0007399 TAS nervous system development
GO:0007411 ISS axon guidance
GO:0007413 ISS axonal fasciculation
GO:0007612 IEA learning
GO:0008046 IEA axon guidance receptor activity
GO:0009887 IEA organ morphogenesis
GO:0016310 ISS phosphorylation
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0018108 ISS peptidyl-tyrosine phosphorylation
GO:0021631 IEA optic nerve morphogenesis
GO:0021952 IEA central nervous system projection neuron axonogenesis
GO:0022038 ISS corpus callosum development
GO:0030424 ISS axon
GO:0030425 ISS dendrite
GO:0031290 IEA retinal ganglion cell axon guidance
GO:0042472 ISS inner ear morphogenesis
GO:0043025 IEA neuronal cell body
GO:0048013 ISS:IEA ephrin receptor signaling pathway
GO:0048168 IEA regulation of neuronal synaptic plasticity
GO:0048170 IEA positive regulation of long-term neuronal synaptic plasticity
GO:0048593 IEA camera-type eye morphogenesis
GO:0050770 IEA regulation of axonogenesis
GO:0050771 IEA negative regulation of axonogenesis
GO:0050878 ISS regulation of body fluid levels
GO:0051965 ISS positive regulation of synapse assembly
GO:0060021 ISS palate development
GO:0060996 ISS dendritic spine development
GO:0060997 ISS dendritic spine morphogenesis
GO:0071679 ISS commissural neuron axon guidance

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000105846 Ephb2-003 protein_coding Mus_musculus 0 4189
ENSMUST00000105845 Ephb2-001 protein_coding Mus_musculus 0 4169
ENSMUST00000059287 Ephb2-002 protein_coding Mus_musculus 0 4156
ENSDART00000043756 ephb2b-001 protein_coding Danio_rerio 0 1993
ENSMUST00000144573 Ephb2-005 retained_intron Mus_musculus 0 1133
ENSMUST00000156558 Ephb2-004 protein_coding Mus_musculus 0 1074
ENSMUST00000166239 Ephb4-201 protein_coding Mus_musculus 0 710
ENSMUST00000111054 Ephb4-003 protein_coding Mus_musculus 0 710
ENSMUST00000111055 Ephb4-002 protein_coding Mus_musculus 0 710
ENSMUST00000144296 Ephb4-004 nonsense_mediated_decay Mus_musculus 0 710
ENSMUST00000061244 Ephb4-001 protein_coding Mus_musculus 0 710
ENSMUST00000151502 Ephb2-006 retained_intron Mus_musculus 0 623
ENSDART00000037292 epha4b-201 protein_coding Danio_rerio 0 477
ENSMUST00000006614 Epha2-001 protein_coding Mus_musculus 0 442
ENSMUST00000068860 Epha6-001 protein_coding Mus_musculus 0 274

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