ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Transcript Info
Description:
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000006614 Epha2-001 ENSMUSG00000006445 10090 + 4:141301240-141329384 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; C166Tie2+ ECmESENSMUST00000006614
Transcript ID C166 Tie2+ EC mES
ENSMUST00000006614 31.986±5.89 31.199±26.46 0.392±0.04

Conserved Regions

Not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001501 IMP skeletal system development
GO:0001525 IEA angiogenesis
GO:0001568 IMP blood vessel development
GO:0001570 IMP vasculogenesis
GO:0001649 IMP osteoblast differentiation
GO:0004714 ISS transmembrane receptor protein tyrosine kinase activity
GO:0005003 IEA ephrin receptor activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005886 IEA plasma membrane
GO:0005887 ISS integral component of plasma membrane
GO:0005925 ISS focal adhesion
GO:0007155 IEA cell adhesion
GO:0008630 IEA intrinsic apoptotic signaling pathway in response to DNA damage
GO:0009986 IEA cell surface
GO:0010591 ISS regulation of lamellipodium assembly
GO:0014028 IGI notochord formation
GO:0016477 ISS cell migration
GO:0018108 IEA peptidyl-tyrosine phosphorylation
GO:0021915 IMP neural tube development
GO:0030182 IDA neuron differentiation
GO:0030216 IEA keratinocyte differentiation
GO:0030316 IDA osteoclast differentiation
GO:0031256 ISS leading edge membrane
GO:0032863 ISS activation of Rac GTPase activity
GO:0033598 IMP mammary gland epithelial cell proliferation
GO:0033628 ISS regulation of cell adhesion mediated by integrin
GO:0036342 IMP post-anal tail morphogenesis
GO:0042995 IEA cell projection
GO:0043491 ISS protein kinase B signaling
GO:0043535 IDA regulation of blood vessel endothelial cell migration
GO:0045765 IDA regulation of angiogenesis
GO:0046849 IMP bone remodeling
GO:0048013 IDA ephrin receptor signaling pathway
GO:0048320 IMP axial mesoderm formation
GO:0048570 IMP notochord morphogenesis
GO:0051898 ISS negative regulation of protein kinase B signaling
GO:0060035 IMP notochord cell development
GO:0060326 ISS cell chemotaxis
GO:0060444 IMP branching involved in mammary gland duct morphogenesis
GO:0070309 IDA lens fiber cell morphogenesis
GO:0070372 IEA regulation of ERK1 and ERK2 cascade
GO:0070848 ISS response to growth factor
GO:0090004 ISS positive regulation of establishment of protein localization to plasma membrane

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSDART00000037292 epha4b-201 protein_coding Danio_rerio 0 394
ENSDART00000098632 epha4a-201 protein_coding Danio_rerio 0 350
ENSDART00000128457 ephb1-201 protein_coding Danio_rerio 0 318
ENSDART00000145347 ephb1-001 protein_coding Danio_rerio 0 318
ENSDART00000149895 epha4a-001 protein_coding Danio_rerio 0 231
ENSDART00000004338 epha4l-001 protein_coding Danio_rerio 0.000000000001 81
ENSDART00000148563 epha4a-002 protein_coding Danio_rerio 0.000002 60
ENST00000358173 EPHB4-001 protein_coding Homo_sapiens 0 364
ENST00000358432 EPHA2-001 protein_coding Homo_sapiens 0 3314
ENST00000360620 EPHB4-005 protein_coding Homo_sapiens 0 364
ENST00000374627 EPHB2-004 protein_coding Homo_sapiens 0 442
ENST00000374630 EPHB2-003 protein_coding Homo_sapiens 0 442
ENST00000374632 EPHB2-002 protein_coding Homo_sapiens 0 442
ENST00000400191 EPHB2-001 protein_coding Homo_sapiens 0 442
ENST00000461614 EPHA2-002 processed_transcript Homo_sapiens 0 752
ENST00000467515 EPHB4-008 retained_intron Homo_sapiens 0 279
ENST00000478459 EPHB4-007 retained_intron Homo_sapiens 0 359
ENST00000487222 EPHB4-002 retained_intron Homo_sapiens 0 364
ENST00000611929 EPHA2-201 protein_coding Homo_sapiens 0 3308
ENST00000616502 EPHB4-201 protein_coding Homo_sapiens 0 364

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