ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Transcript Info
Description: Mitogen-activated protein kinase kinase kinase MLT
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000375213 ZAK-001 ENSG00000091436 9606 + 2:173075959-173268010 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHUVECENST00000375213
Transcript ID BECs HAoEC HHSEC HUVEC
ENST00000375213 0.777±0.00 1.894±0.82 0.624±0.00 1.628±0.74

Conserved Regions

Not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000075 IDA cell cycle checkpoint
GO:0000077 IMP DNA damage checkpoint
GO:0000186 TAS activation of MAPKK activity
GO:0000287 IDA magnesium ion binding
GO:0004672 IEA protein kinase activity
GO:0004674 IDA protein serine/threonine kinase activity
GO:0004709 IDA MAP kinase kinase kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005515 IPI:IEA protein binding
GO:0005524 IEA:IDA ATP binding
GO:0005634 IEA nucleus
GO:0005737 ISS cytoplasm
GO:0006468 IEA:IDA protein phosphorylation
GO:0006950 NAS response to stress
GO:0007010 IEA cytoskeleton organization
GO:0007050 IMP cell cycle arrest
GO:0007257 IDA activation of JUN kinase activity
GO:0008219 NAS cell death
GO:0008283 NAS cell proliferation
GO:0009314 IDA response to radiation
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0030154 NAS cell differentiation
GO:0035556 IDA intracellular signal transduction
GO:0043065 IDA positive regulation of apoptotic process
GO:0044822 IDA poly(A) RNA binding

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000090824 Zak-001 protein_coding Mus_musculus 0 2830
ENSMUST00000135469 Zak-002 protein_coding Mus_musculus 0 1541
ENSMUST00000112073 Zak-003 retained_intron Mus_musculus 0 1537
ENSMUST00000150126 Zak-004 retained_intron Mus_musculus 0 1375
ENSMUST00000135204 Zak-005 retained_intron Mus_musculus 0 588
ENSDART00000151393 zak-002 protein_coding Danio_rerio 0 422
ENSDART00000065551 zak-001 protein_coding Danio_rerio 0 422
ENSMUST00000144111 Zak-006 protein_coding Mus_musculus 0 399

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