Warning (512): _cake_core_ cache was unable to write 'cake_dev_eng' to File cache [CORE/Cake/Cache/Cache.php, line 323]
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                ),
                E_USER_WARNING
            );
$key = 'cake_dev_eng'
$value = array(
	'LC_MESSAGES' => array()
)
$config = '_cake_core_'
$settings = array(
	'prefix' => '*****',
	'engine' => 'File',
	'path' => '/var/www/angiogenes/app/tmp/cache/persistent/',
	'serialize' => true,
	'duration' => (int) 10,
	'lock' => true,
	'isWindows' => false,
	'mask' => (int) 436,
	'probability' => (int) 100,
	'groups' => array()
)
$success = false
Cache::write() - CORE/Cake/Cache/Cache.php, line 323
I18n::translate() - CORE/Cake/I18n/I18n.php, line 237
__d - CORE/Cake/basics.php, line 617
Cache::write() - CORE/Cake/Cache/Cache.php, line 321
DataSource::listSources() - CORE/Cake/Model/Datasource/DataSource.php, line 110
Mysql::listSources() - CORE/Cake/Model/Datasource/Database/Mysql.php, line 219
Model::setSource() - CORE/Cake/Model/Model.php, line 1142
Model::getDataSource() - CORE/Cake/Model/Model.php, line 3551
Model::__call() - CORE/Cake/Model/Model.php, line 808
Transcript::findByid() - APP/Controller/TranscriptController.php, line 303
TranscriptController::show() - APP/Controller/TranscriptController.php, line 303
ReflectionMethod::invokeArgs() - [internal], line ??
Controller::invokeAction() - CORE/Cake/Controller/Controller.php, line 490
Dispatcher::_invoke() - CORE/Cake/Routing/Dispatcher.php, line 191
Dispatcher::dispatch() - CORE/Cake/Routing/Dispatcher.php, line 165
[main] - APP/webroot/index.php, line 108

Warning (512): _cake_model_ cache was unable to write 'default_angiogenes_list' to File cache [CORE/Cake/Cache/Cache.php, line 323]
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                ),
                E_USER_WARNING
            );
$key = 'default_angiogenes_list'
$value = null
$config = '_cake_model_'
$settings = array(
	'prefix' => '*****',
	'engine' => 'File',
	'path' => '/var/www/angiogenes/app/tmp/cache/models/',
	'serialize' => true,
	'duration' => (int) 10,
	'lock' => true,
	'isWindows' => false,
	'mask' => (int) 436,
	'probability' => (int) 100,
	'groups' => array()
)
$success = false
Cache::write() - CORE/Cake/Cache/Cache.php, line 323
DataSource::listSources() - CORE/Cake/Model/Datasource/DataSource.php, line 110
Mysql::listSources() - CORE/Cake/Model/Datasource/Database/Mysql.php, line 219
Model::setSource() - CORE/Cake/Model/Model.php, line 1142
Model::getDataSource() - CORE/Cake/Model/Model.php, line 3551
Model::__call() - CORE/Cake/Model/Model.php, line 808
Transcript::findByid() - APP/Controller/TranscriptController.php, line 303
TranscriptController::show() - APP/Controller/TranscriptController.php, line 303
ReflectionMethod::invokeArgs() - [internal], line ??
Controller::invokeAction() - CORE/Cake/Controller/Controller.php, line 490
Dispatcher::_invoke() - CORE/Cake/Routing/Dispatcher.php, line 191
Dispatcher::dispatch() - CORE/Cake/Routing/Dispatcher.php, line 165
[main] - APP/webroot/index.php, line 108

Warning (512): _cake_model_ cache was unable to write 'default_angiogenes_list' to File cache [CORE/Cake/Cache/Cache.php, line 323]
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                ),
                E_USER_WARNING
            );
$key = 'default_angiogenes_list'
$value = array(
	(int) 0 => 'diffexp',
	(int) 1 => 'experiment',
	(int) 2 => 'expressed_transcripts',
	(int) 3 => 'genes',
	(int) 4 => 'go_annotations',
	(int) 5 => 'homologues',
	(int) 6 => 'repeats',
	(int) 7 => 'study',
	(int) 8 => 'synonyms',
	(int) 9 => 'transcripts'
)
$config = '_cake_model_'
$settings = array(
	'prefix' => '*****',
	'engine' => 'File',
	'path' => '/var/www/angiogenes/app/tmp/cache/models/',
	'serialize' => true,
	'duration' => (int) 10,
	'lock' => true,
	'isWindows' => false,
	'mask' => (int) 436,
	'probability' => (int) 100,
	'groups' => array()
)
$success = false
Cache::write() - CORE/Cake/Cache/Cache.php, line 323
DataSource::listSources() - CORE/Cake/Model/Datasource/DataSource.php, line 110
Mysql::listSources() - CORE/Cake/Model/Datasource/Database/Mysql.php, line 236
Model::setSource() - CORE/Cake/Model/Model.php, line 1142
Model::getDataSource() - CORE/Cake/Model/Model.php, line 3551
Model::__call() - CORE/Cake/Model/Model.php, line 808
Transcript::findByid() - APP/Controller/TranscriptController.php, line 303
TranscriptController::show() - APP/Controller/TranscriptController.php, line 303
ReflectionMethod::invokeArgs() - [internal], line ??
Controller::invokeAction() - CORE/Cake/Controller/Controller.php, line 490
Dispatcher::_invoke() - CORE/Cake/Routing/Dispatcher.php, line 191
Dispatcher::dispatch() - CORE/Cake/Routing/Dispatcher.php, line 165
[main] - APP/webroot/index.php, line 108

Warning (512): _cake_model_ cache was unable to write 'default_angiogenes_transcripts' to File cache [CORE/Cake/Cache/Cache.php, line 323]
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                ),
                E_USER_WARNING
            );
$key = 'default_angiogenes_transcripts'
$value = null
$config = '_cake_model_'
$settings = array(
	'prefix' => '*****',
	'engine' => 'File',
	'path' => '/var/www/angiogenes/app/tmp/cache/models/',
	'serialize' => true,
	'duration' => (int) 10,
	'lock' => true,
	'isWindows' => false,
	'mask' => (int) 436,
	'probability' => (int) 100,
	'groups' => array()
)
$success = false
Cache::write() - CORE/Cake/Cache/Cache.php, line 323
DataSource::_cacheDescription() - CORE/Cake/Model/Datasource/DataSource.php, line 310
DataSource::describe() - CORE/Cake/Model/Datasource/DataSource.php, line 135
Mysql::describe() - CORE/Cake/Model/Datasource/Database/Mysql.php, line 332
Model::schema() - CORE/Cake/Model/Model.php, line 1372
DboSource::fields() - CORE/Cake/Model/Datasource/DboSource.php, line 2491
DboSource::read() - CORE/Cake/Model/Datasource/DboSource.php, line 1054
Model::_readDataSource() - CORE/Cake/Model/Model.php, line 2947
Model::find() - CORE/Cake/Model/Model.php, line 2919
DboSource::query() - CORE/Cake/Model/Datasource/DboSource.php, line 597
Model::__call() - CORE/Cake/Model/Model.php, line 808
Transcript::findByid() - APP/Controller/TranscriptController.php, line 303
TranscriptController::show() - APP/Controller/TranscriptController.php, line 303
ReflectionMethod::invokeArgs() - [internal], line ??
Controller::invokeAction() - CORE/Cake/Controller/Controller.php, line 490
Dispatcher::_invoke() - CORE/Cake/Routing/Dispatcher.php, line 191
Dispatcher::dispatch() - CORE/Cake/Routing/Dispatcher.php, line 165

Warning (512): _cake_model_ cache was unable to write 'default_angiogenes_transcripts' to File cache [CORE/Cake/Cache/Cache.php, line 323]
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                ),
                E_USER_WARNING
            );
$key = 'default_angiogenes_transcripts'
$value = array(
	'id' => array(
		'type' => 'string',
		'null' => false,
		'default' => null,
		'length' => (int) 32,
		'key' => 'primary',
		'collate' => 'latin1_swedish_ci',
		'charset' => 'latin1'
	),
	'fk_gene_id' => array(
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		'null' => false,
		'default' => null,
		'length' => (int) 32,
		'key' => 'index',
		'collate' => 'latin1_swedish_ci',
		'charset' => 'latin1'
	),
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		'null' => true,
		'default' => null,
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		'collate' => 'latin1_swedish_ci',
		'charset' => 'latin1'
	),
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		'charset' => 'latin1'
	),
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		'default' => null,
		'length' => (int) 64,
		'collate' => 'latin1_swedish_ci',
		'charset' => 'latin1'
	),
	'chromosome' => array(
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		'null' => false,
		'default' => null,
		'length' => (int) 64,
		'key' => 'index',
		'collate' => 'latin1_swedish_ci',
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	'strand' => array(
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		'length' => (int) 64,
		'collate' => 'latin1_swedish_ci',
		'charset' => 'latin1'
	),
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		'type' => 'string',
		'null' => true,
		'default' => null,
		'length' => (int) 64,
		'collate' => 'latin1_swedish_ci',
		'charset' => 'latin1'
	),
	'transcript_biotype' => array(
		'type' => 'string',
		'null' => true,
		'default' => null,
		'length' => (int) 128,
		'collate' => 'latin1_swedish_ci',
		'charset' => 'latin1'
	),
	'annotation_version' => array(
		'type' => 'string',
		'null' => false,
		'default' => null,
		'length' => (int) 8,
		'collate' => 'latin1_swedish_ci',
		'charset' => 'latin1'
	)
)
$config = '_cake_model_'
$settings = array(
	'prefix' => '*****',
	'engine' => 'File',
	'path' => '/var/www/angiogenes/app/tmp/cache/models/',
	'serialize' => true,
	'duration' => (int) 10,
	'lock' => true,
	'isWindows' => false,
	'mask' => (int) 436,
	'probability' => (int) 100,
	'groups' => array()
)
$success = false
Cache::write() - CORE/Cake/Cache/Cache.php, line 323
DataSource::_cacheDescription() - CORE/Cake/Model/Datasource/DataSource.php, line 310
Mysql::describe() - CORE/Cake/Model/Datasource/Database/Mysql.php, line 372
Model::schema() - CORE/Cake/Model/Model.php, line 1372
DboSource::fields() - CORE/Cake/Model/Datasource/DboSource.php, line 2491
DboSource::read() - CORE/Cake/Model/Datasource/DboSource.php, line 1054
Model::_readDataSource() - CORE/Cake/Model/Model.php, line 2947
Model::find() - CORE/Cake/Model/Model.php, line 2919
DboSource::query() - CORE/Cake/Model/Datasource/DboSource.php, line 597
Model::__call() - CORE/Cake/Model/Model.php, line 808
Transcript::findByid() - APP/Controller/TranscriptController.php, line 303
TranscriptController::show() - APP/Controller/TranscriptController.php, line 303
ReflectionMethod::invokeArgs() - [internal], line ??
Controller::invokeAction() - CORE/Cake/Controller/Controller.php, line 490
Dispatcher::_invoke() - CORE/Cake/Routing/Dispatcher.php, line 191
Dispatcher::dispatch() - CORE/Cake/Routing/Dispatcher.php, line 165
[main] - APP/webroot/index.php, line 108

ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

• HOME
• GENES
• TRANSCRIPTS
• HELP
• CONTACT

Transcript Info
Description:	neurexin 2
Transcript Accession	Transcript Name	Contained in Gene	Tax ID	Strand	Position	Biotype
ENST00000377559	NRXN2-002	ENSG00000110076	9606	-	11:64606174-64723188	protein_coding

Expression Patterns Split around values. Cell Line Name Tissue Condition Heat Map Numeric Values Transcript ID HAoEC HUVEC ENST00000377559 0.387±0.15 0.012±0.00

Conserved Regions
Not located within a conserved region.

Gene Ontology
GO ID	Evidence Type	GO Description
GO:0005246	ISS	calcium channel regulator activity
GO:0005515	IEA	protein binding
GO:0007158	TAS	neuron cell-cell adhesion
GO:0007268	ISS	synaptic transmission
GO:0007269	ISS	neurotransmitter secretion
GO:0007416	ISS	synapse assembly
GO:0016021	IEA	integral component of membrane
GO:0030534	IMP	adult behavior
GO:0035176	IMP	social behavior
GO:0042297	IMP	vocal learning
GO:0046872	IEA	metal ion binding
GO:0050839	ISS	cell adhesion molecule binding
GO:0071625	IMP	vocalization behavior
GO:0097104	ISS	postsynaptic membrane assembly
GO:0097109	ISS	neuroligin family protein binding
GO:0097116	ISS	gephyrin clustering
GO:0097118	ISS	neuroligin clustering
GO:0097119	ISS	postsynaptic density protein 95 clustering

Homologs
ENSEMBL Accession	Gene Name	Biotype	Species	E-Value	Bit Score
ENSMUST00000113461	Nrxn2-008	protein_coding	Mus_musculus	0	7354
ENSMUST00000113462	Nrxn2-001	protein_coding	Mus_musculus	0	3832
ENSMUST00000137166	Nrxn2-013	protein_coding	Mus_musculus	0	3736
ENSMUST00000077182	Nrxn2-201	protein_coding	Mus_musculus	0	3677
ENSMUST00000113458	Nrxn2-004	protein_coding	Mus_musculus	0	2222
ENSMUST00000150792	Nrxn2-005	retained_intron	Mus_musculus	0	2089
ENSMUST00000128272	Nrxn2-002	retained_intron	Mus_musculus	0	1363
ENSMUST00000140435	Nrxn2-006	retained_intron	Mus_musculus	0	1284
ENSMUST00000113459	Nrxn2-003	protein_coding	Mus_musculus	0	1068
ENSMUST00000124815	Nrxn2-011	processed_transcript	Mus_musculus	0	983
ENSMUST00000167103	Nrxn3-003	nonsense_mediated_decay	Mus_musculus	0	852
ENSMUST00000157014	Nrxn2-007	processed_transcript	Mus_musculus	0	845
ENSMUST00000163134	Nrxn3-001	protein_coding	Mus_musculus	0	761
ENSMUST00000190626	Nrxn3-012	nonsense_mediated_decay	Mus_musculus	0	699
ENSMUST00000155158	Nrxn2-014	protein_coding	Mus_musculus	0	682
ENSMUST00000057634	Nrxn3-002	protein_coding	Mus_musculus	0	664
ENSMUST00000137821	Nrxn2-012	protein_coding	Mus_musculus	0	592
ENSMUST00000154580	Nrxn2-010	processed_transcript	Mus_musculus	0	582
ENSMUST00000167887	Nrxn3-201	protein_coding	Mus_musculus	0	531
ENSDART00000111239	nrxn1a-202	protein_coding	Danio_rerio	1e-33	150
ENSDART00000088178	nrxn1a-201	protein_coding	Danio_rerio	1e-33	150
ENSDART00000056256	nrxn1a-003	protein_coding	Danio_rerio	1e-33	150
ENSDART00000088159	nrxn1a-002	protein_coding	Danio_rerio	1e-33	150
ENSDART00000093094	nrxn1a-001	protein_coding	Danio_rerio	1e-33	150

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                ),
                E_USER_WARNING
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	'String' => '/var/www/angiogenes/lib/Cake/Utility/String.php',
	'Dispatcher' => '/var/www/angiogenes/lib/Cake/Routing/Dispatcher.php',
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	'CakeRequest' => '/var/www/angiogenes/lib/Cake/Network/CakeRequest.php',
	'CakeResponse' => '/var/www/angiogenes/lib/Cake/Network/CakeResponse.php',
	'CakeEvent' => '/var/www/angiogenes/lib/Cake/Event/CakeEvent.php',
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	'PluginShortRoute' => '/var/www/angiogenes/lib/Cake/Routing/Route/PluginShortRoute.php',
	'TranscriptController' => '/var/www/angiogenes/app/Controller/TranscriptController.php',
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	'ConnectionManager' => '/var/www/angiogenes/lib/Cake/Model/ConnectionManager.php',
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	'ViewBlock' => '/var/www/angiogenes/lib/Cake/View/ViewBlock.php',
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	'Helper' => '/var/www/angiogenes/lib/Cake/View/Helper.php',
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$config = '_cake_core_'
$settings = array(
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	'serialize' => true,
	'duration' => (int) 10,
	'lock' => true,
	'isWindows' => false,
	'mask' => (int) 436,
	'probability' => (int) 100,
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)
$success = false
Cache::write() - CORE/Cake/Cache/Cache.php, line 323
App::shutdown() - CORE/Cake/Core/App.php, line 899
[main] - [internal], line ??

Warning (512): _cake_core_ cache was unable to write 'method_cache' to File cache [CORE/Cake/Cache/Cache.php, line 323]
Code Context
                ),
                E_USER_WARNING
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		'9a798879191c21ec35c3dee0b33210e1' => array(
			(int) 0 => '`Transcript`.`id`',
			(int) 1 => '`Transcript`.`fk_gene_id`',
			(int) 2 => '`Transcript`.`transcript_version`',
			(int) 3 => '`Transcript`.`tax_id`',
			(int) 4 => '`Transcript`.`assembly`',
			(int) 5 => '`Transcript`.`chromosome`',
			(int) 6 => '`Transcript`.`strand`',
			(int) 7 => '`Transcript`.`start`',
			(int) 8 => '`Transcript`.`end`',
			(int) 9 => '`Transcript`.`transcript_name`',
			(int) 10 => '`Transcript`.`transcript_source`',
			(int) 11 => '`Transcript`.`transcript_biotype`',
			(int) 12 => '`Transcript`.`annotation_version`'
		)
	)
)
$config = '_cake_core_'
$settings = array(
	'prefix' => '*****',
	'engine' => 'File',
	'path' => '/var/www/angiogenes/app/tmp/cache/persistent/',
	'serialize' => true,
	'duration' => (int) 10,
	'lock' => true,
	'isWindows' => false,
	'mask' => (int) 436,
	'probability' => (int) 100,
	'groups' => array()
)
$success = false
Cache::write() - CORE/Cake/Cache/Cache.php, line 323
DboSource::__destruct() - CORE/Cake/Model/Datasource/DboSource.php, line 3539
[main] - [internal], line ??