Transcript Info |
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Description: | RAB guanine nucleotide exchange factor (GEF) 1 | |||||
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Transcript Accession | Transcript Name | Contained in Gene | Tax ID | Strand | Position | Biotype |
ENST00000380828 ![]() |
RABGEF1-201 |
ENSG00000154710 ![]() |
9606 | + |
7:66755882-66811459 |
protein_coding |
Expression PatternsNo expression data. |
Conserved Regions |
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Not located within a conserved region. |
Gene Ontology | ||
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GO ID | Evidence Type | GO Description |
GO:0001933 | IEA | negative regulation of protein phosphorylation |
GO:0002686 | IEA | negative regulation of leukocyte migration |
GO:0003677 | IEA | DNA binding |
GO:0004842 | IEA | ubiquitin-protein transferase activity |
GO:0005515 | IPI | protein binding |
GO:0005769 | IMP | early endosome |
GO:0006612 | IMP | protein targeting to membrane |
GO:0006897 | IEA | endocytosis |
GO:0008270 | IEA | zinc ion binding |
GO:0016567 | IEA | protein ubiquitination |
GO:0017112 | IDA | Rab guanyl-nucleotide exchange factor activity |
GO:0017137 | IPI | Rab GTPase binding |
GO:0031982 | IEA | vesicle |
GO:0032851 | IDA | positive regulation of Rab GTPase activity |
GO:0033004 | IEA | negative regulation of mast cell activation |
GO:0043305 | IEA | negative regulation of mast cell degranulation |
GO:0046580 | IEA | negative regulation of Ras protein signal transduction |
GO:0048261 | IEA | negative regulation of receptor-mediated endocytosis |
GO:0050728 | IEA | negative regulation of inflammatory response |
GO:0060368 | IEA | regulation of Fc receptor mediated stimulatory signaling pathway |
GO:1900165 | IEA | negative regulation of interleukin-6 secretion |
GO:1900235 | IEA | negative regulation of Kit signaling pathway |
Homologs | |||||
ENSEMBL Accession | Gene Name | Biotype | Species | E-Value | Bit Score |
ENSMUST00000026390
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Rabgef1-002 | protein_coding | Mus_musculus | 0 | 1895 |
ENSMUST00000119797
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Rabgef1-001 | protein_coding | Mus_musculus | 0 | 1892 |
ENSMUST00000148264
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Rabgef1-003 | protein_coding | Mus_musculus | 0 | 944 |
ENSMUST00000119027
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Rabgef1-004 | protein_coding | Mus_musculus | 0 | 841 |
ENSMUST00000147493
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Rabgef1-007 | retained_intron | Mus_musculus | 0 | 501 |
ENSMUST00000143727
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Rabgef1-005 | retained_intron | Mus_musculus | 0 | 444 |