ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Transcript Info
Description: GEN1 Holliday junction 5' flap endonuclease
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000381254 GEN1-201 ENSG00000178295 9606 + 2:17754147-17785365 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000381254
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000381254 0.807±0.01 1.826±1.75 1.129±0.00 2.504±0.00 2.655±2.39

Conserved Regions

Not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000724 IMP double-strand break repair via homologous recombination
GO:0000737 IMP DNA catabolic process, endonucleolytic
GO:0003677 IEA DNA binding
GO:0003824 IEA catalytic activity
GO:0004518 IEA nuclease activity
GO:0005634 IEA nucleus
GO:0005813 IDA centrosome
GO:0006281 IEA DNA repair
GO:0008821 IMP crossover junction endodeoxyribonuclease activity
GO:0010824 IMP regulation of centrosome duplication
GO:0046872 IEA metal ion binding
GO:0070062 IDA extracellular vesicular exosome
GO:0071139 IMP resolution of recombination intermediates
GO:0071140 IMP resolution of mitotic recombination intermediates
GO:0090267 IMP positive regulation of mitotic cell cycle spindle assembly checkpoint
GO:0090305 IEA nucleic acid phosphodiester bond hydrolysis

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000166117 Gen1-201 protein_coding Mus_musculus 0 1801
ENSMUST00000193399 Mfsd7b-006 retained_intron Mus_musculus 0.000009 58

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