ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Transcript Info
Description: lysyl oxidase-like 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000389131 LOXL2-001 ENSG00000134013 9606 - 8:23297189-23404240 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHMVEC-DHUVECENST00000389131
Transcript ID BECs HAoEC HMVEC-D HUVEC
ENST00000389131 29.372±17.86 151.788±94.49 135.902±0.00 111.758±80.47

Conserved Regions

Not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001666 ISS response to hypoxia
GO:0001837 IDA epithelial to mesenchymal transition
GO:0001935 IMP endothelial cell proliferation
GO:0002040 IMP sprouting angiogenesis
GO:0003682 IDA chromatin binding
GO:0003714 IDA transcription corepressor activity
GO:0004720 IDA protein-lysine 6-oxidase activity
GO:0005044 IEA scavenger receptor activity
GO:0005507 IEA copper ion binding
GO:0005515 IPI protein binding
GO:0005604 ISS basement membrane
GO:0005615 IDA extracellular space
GO:0005634 IDA nucleus
GO:0005694 IEA chromosome
GO:0006351 IEA transcription, DNA-templated
GO:0006464 IDA cellular protein modification process
GO:0006898 IEA receptor-mediated endocytosis
GO:0007155 TAS cell adhesion
GO:0007568 TAS aging
GO:0009055 TAS electron carrier activity
GO:0016020 IEA membrane
GO:0016570 IDA histone modification
GO:0016641 IEA oxidoreductase activity, acting on the CH-NH2 group of donors, oxygen as acceptor
GO:0018277 IDA protein deamination
GO:0030199 IMP collagen fibril organization
GO:0032332 ISS positive regulation of chondrocyte differentiation
GO:0035064 IDA methylated histone binding
GO:0043542 IMP endothelial cell migration
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0046688 IDA response to copper ion
GO:0055114 IDA:IEA oxidation-reduction process
GO:0070492 IDA oligosaccharide binding

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000100420 Loxl2-002 protein_coding Mus_musculus 0 2296
ENSMUST00000022660 Loxl2-001 protein_coding Mus_musculus 0 2296
ENSMUST00000111062 Gm21451-001 transcribed_unprocessed_pseudogene Mus_musculus 0 2115
ENSMUST00000179116 Gm28049-001 protein_coding Mus_musculus 0 283

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