ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Transcript Info
Description: methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000394053 MTHFD2-001 ENSG00000065911 9606 + 2:74198562-74217565 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; HAoECHUVECENST00000394053
Transcript ID HAoEC HUVEC
ENST00000394053 11.451±0.58 6.514±1.23

Conserved Regions

Not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000287 IDA magnesium ion binding
GO:0003824 IEA catalytic activity
GO:0004477 IBA methenyltetrahydrofolate cyclohydrolase activity
GO:0004487 IDA methylenetetrahydrofolate dehydrogenase (NAD+) activity
GO:0004488 IDA:IEA methylenetetrahydrofolate dehydrogenase (NADP+) activity
GO:0005615 IDA extracellular space
GO:0005739 IBA mitochondrion
GO:0006730 IBA one-carbon metabolic process
GO:0009396 IEA folic acid-containing compound biosynthetic process
GO:0042301 IDA phosphate ion binding
GO:0046653 IDA tetrahydrofolate metabolic process
GO:0055114 IEA oxidation-reduction process

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000005810 Mthfd2-001 protein_coding Mus_musculus 0 1203
ENSMUST00000141044 Mthfd2-004 processed_transcript Mus_musculus 0 294
ENSMUST00000173269 Neu1-002 retained_intron Mus_musculus 0.000002 60

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