| Transcript ID | BECs | HAoEC | HHSEC | HMVEC-D | HUVEC |
|---|---|---|---|---|---|
| ENST00000405885 | 10.985±2.29 | 5.103±2.53 | 15.839±0.00 | 13.880±0.00 | 4.233±2.62 |
Transcript Info |
||||||
| Description: | interferon regulatory factor 1 | |||||
|---|---|---|---|---|---|---|
| Transcript Accession | Transcript Name | Contained in Gene | Tax ID | Strand | Position | Biotype |
|
ENST00000405885 |
IRF1-008 |
ENSG00000125347 |
9606 | - |
5:132483086-132490262 |
protein_coding |
Expression Patterns
|
Conserved Regions |
|---|
| Not located within a conserved region. |
Gene Ontology | ||
|---|---|---|
| GO ID | Evidence Type | GO Description |
| GO:0000790 | IDA | nuclear chromatin |
| GO:0000975 | IEA | regulatory region DNA binding |
| GO:0000978 | IDA | RNA polymerase II core promoter proximal region sequence-specific DNA binding |
| GO:0002819 | TAS | regulation of adaptive immune response |
| GO:0003677 | TAS | DNA binding |
| GO:0005515 | IPI | protein binding |
| GO:0005634 | TAS | nucleus |
| GO:0005654 | TAS | nucleoplasm |
| GO:0005737 | ISS | cytoplasm |
| GO:0005829 | TAS | cytosol |
| GO:0006366 | TAS | transcription from RNA polymerase II promoter |
| GO:0006915 | IDA | apoptotic process |
| GO:0007050 | IDA | cell cycle arrest |
| GO:0007596 | TAS | blood coagulation |
| GO:0008285 | TAS | negative regulation of cell proliferation |
| GO:0019221 | TAS | cytokine-mediated signaling pathway |
| GO:0032481 | ISS | positive regulation of type I interferon production |
| GO:0032728 | IMP | positive regulation of interferon-beta production |
| GO:0034124 | ISS | regulation of MyD88-dependent toll-like receptor signaling pathway |
| GO:0035458 | IDA | cellular response to interferon-beta |
| GO:0045088 | TAS | regulation of innate immune response |
| GO:0045590 | ISS | negative regulation of regulatory T cell differentiation |
| GO:0045892 | IMP | negative regulation of transcription, DNA-templated |
| GO:0045893 | IMP | positive regulation of transcription, DNA-templated |
| GO:0051607 | IDA | defense response to virus |
| GO:0051726 | TAS | regulation of cell cycle |
| GO:0060333 | ISS | interferon-gamma-mediated signaling pathway |
| GO:0060337 | TAS | type I interferon signaling pathway |
| GO:0071260 | IEP | cellular response to mechanical stimulus |
| GO:2000564 | ISS | regulation of CD8-positive, alpha-beta T cell proliferation |
Homologs | |||||
| ENSEMBL Accession | Gene Name | Biotype | Species | E-Value | Bit Score |
|
ENSMUST00000019043
|
Irf1-002 | protein_coding | Mus_musculus | 0 | 1299 |
|
ENSMUST00000108920
|
Irf1-001 | protein_coding | Mus_musculus | 0 | 1277 |
|
ENSMUST00000108922
|
Irf1-008 | protein_coding | Mus_musculus | 0 | 889 |
|
ENSMUST00000140866
|
Irf1-010 | protein_coding | Mus_musculus | 0 | 651 |
|
ENSMUST00000123376
|
Irf1-005 | protein_coding | Mus_musculus | 0 | 647 |
|
ENSMUST00000133291
|
Irf1-006 | protein_coding | Mus_musculus | 0 | 556 |
|
ENSMUST00000138913
|
Irf1-007 | protein_coding | Mus_musculus | 0 | 285 |
|
ENSMUST00000170390
|
Gm17334-201 | protein_coding | Mus_musculus | 4e-35 | 154 |
|
ENSMUST00000142221
|
Irf1-009 | nonsense_mediated_decay | Mus_musculus | 4e-30 | 137 |