ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Transcript Info
Description: nemo-like kinase
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000407008 NLK-001 ENSG00000087095 9606 + 17:28042156-28196381 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHHSECHMVEC-DHUVECENST00000407008
Transcript ID BECs HAoEC HHSEC HMVEC-D HUVEC
ENST00000407008 0.485±0.00 6.795±3.20 2.686±0.00 11.516±0.00 7.793±4.20

Conserved Regions

Not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000165 IEA MAPK cascade
GO:0000287 ISS magnesium ion binding
GO:0004672 TAS:IEA protein kinase activity
GO:0004674 TAS protein serine/threonine kinase activity
GO:0004707 IEA:ISS MAP kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005515 IPI protein binding
GO:0005524 ISS:IEA ATP binding
GO:0005634 ISS nucleus
GO:0005654 TAS nucleoplasm
GO:0005829 TAS cytosol
GO:0006351 IEA transcription, DNA-templated
GO:0006355 ISS regulation of transcription, DNA-templated
GO:0006468 ISS:IEA protein phosphorylation
GO:0007179 IMP transforming growth factor beta receptor signaling pathway
GO:0008134 IPI transcription factor binding
GO:0016055 IEA Wnt signaling pathway
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0018107 ISS peptidyl-threonine phosphorylation
GO:0030178 ISS negative regulation of Wnt signaling pathway
GO:0031625 IPI ubiquitin protein ligase binding
GO:0033136 ISS serine phosphorylation of STAT3 protein
GO:0035556 ISS intracellular signal transduction
GO:0042169 ISS SH2 domain binding
GO:0046777 IEA protein autophosphorylation

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000142739 Nlk-001 protein_coding Mus_musculus 0 5227
ENSMUST00000165271 Nlk-002 retained_intron Mus_musculus 0 1275
ENSMUST00000120843 Nlk-ps1-001 processed_pseudogene Mus_musculus 0 1127
ENSMUST00000165475 Nlk-004 processed_transcript Mus_musculus 0 784
ENSMUST00000170394 Nlk-003 protein_coding Mus_musculus 0 510

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