ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Transcript Info
Description: SMAD family member 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000515385 SMAD1-002 ENSG00000170365 9606 + 4:145482811-145558079 protein_coding

Homo sapiens Ensembl GRCh38

Genome
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Expression Patterns


Heat Map
Numeric Values
Transcript'; HUVECENST00000515385
Transcript ID HUVEC
ENST00000515385 10.800±7.33

Conserved Regions

Not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000165 IEA MAPK cascade
GO:0000979 IEA RNA polymerase II core promoter sequence-specific DNA binding
GO:0001657 IEA ureteric bud development
GO:0001710 IEA mesodermal cell fate commitment
GO:0001822 IEA kidney development
GO:0002051 IEA osteoblast fate commitment
GO:0003700 IDA:IEA sequence-specific DNA binding transcription factor activity
GO:0005057 NAS receptor signaling protein activity
GO:0005515 IPI:IEA protein binding
GO:0005622 NAS:IEA intracellular
GO:0005634 IDA nucleus
GO:0005637 IDA nuclear inner membrane
GO:0005654 TAS nucleoplasm
GO:0005667 IEA transcription factor complex
GO:0005737 IDA cytoplasm
GO:0005739 IDA mitochondrion
GO:0005829 TAS cytosol
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006357 IEA regulation of transcription from RNA polymerase II promoter
GO:0006468 IEA protein phosphorylation
GO:0006954 IEA inflammatory response
GO:0007165 NAS signal transduction
GO:0007179 IEA:NAS transforming growth factor beta receptor signaling pathway
GO:0007183 IDA SMAD protein complex assembly
GO:0007276 IEA gamete generation
GO:0008285 IEA negative regulation of cell proliferation
GO:0009880 ISS embryonic pattern specification
GO:0010243 IEA response to organonitrogen compound
GO:0010628 IDA positive regulation of gene expression
GO:0010656 IEA negative regulation of muscle cell apoptotic process
GO:0016021 NAS integral component of membrane
GO:0019901 IPI protein kinase binding
GO:0030509 ISS BMP signaling pathway
GO:0030618 TAS transforming growth factor beta receptor, pathway-specific cytoplasmic mediator activity
GO:0030901 IEA midbrain development
GO:0030902 IEA hindbrain development
GO:0031053 TAS primary miRNA processing
GO:0042060 IEA wound healing
GO:0042493 IEA response to drug
GO:0042592 IEA homeostatic process
GO:0042802 IPI identical protein binding
GO:0043234 IDA protein complex
GO:0045597 IEA positive regulation of cell differentiation
GO:0045669 IEA positive regulation of osteoblast differentiation
GO:0045944 IC positive regulation of transcription from RNA polymerase II promoter
GO:0046872 IEA metal ion binding
GO:0050775 IEA positive regulation of dendrite morphogenesis
GO:0051216 IEA cartilage development
GO:0060038 IEA cardiac muscle cell proliferation
GO:0060348 IEA bone development
GO:0061036 IEA positive regulation of cartilage development
GO:0070410 IPI co-SMAD binding
GO:0070411 IPI I-SMAD binding
GO:0071407 IEA cellular response to organic cyclic compound
GO:0071773 ISS cellular response to BMP stimulus
GO:1901522 ISS positive regulation of transcription from RNA polymerase II promoter involved in cellular response to chemical stimulus

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000066091 Smad1-001 protein_coding Mus_musculus 0 1869
ENSMUST00000109885 Smad1-002 protein_coding Mus_musculus 0 1555
ENSMUST00000066081 Smad1-003 protein_coding Mus_musculus 0 830
ENSMUST00000029371 Smad9-001 protein_coding Mus_musculus 0 346

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