ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Transcript Info
Description: aspartate beta-hydroxylase
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000518068 ASPH-008 ENSG00000198363 9606 - 8:61624539-61714568 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; BECsHAoECHMVEC-DHUVECENST00000518068
Transcript ID BECs HAoEC HMVEC-D HUVEC
ENST00000518068 10.778±0.00 11.318±2.27 23.215±0.00 12.447±8.05

Conserved Regions

Not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004597 IEA peptide-aspartate beta-dioxygenase activity
GO:0005198 TAS structural molecule activity
GO:0005509 NAS calcium ion binding
GO:0005513 TAS detection of calcium ion
GO:0005515 IPI protein binding
GO:0005783 IDA endoplasmic reticulum
GO:0005789 NAS endoplasmic reticulum membrane
GO:0005886 IDA plasma membrane
GO:0006936 TAS muscle contraction
GO:0008307 TAS structural constituent of muscle
GO:0009055 TAS electron carrier activity
GO:0010524 IDA positive regulation of calcium ion transport into cytosol
GO:0010649 TAS regulation of cell communication by electrical coupling
GO:0010880 TAS regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
GO:0010881 ISS regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
GO:0014701 TAS junctional sarcoplasmic reticulum membrane
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0030176 IDA integral component of endoplasmic reticulum membrane
GO:0031585 IDA regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity
GO:0032237 IDA activation of store-operated calcium channel activity
GO:0032541 IDA cortical endoplasmic reticulum
GO:0033017 TAS sarcoplasmic reticulum membrane
GO:0033018 TAS sarcoplasmic reticulum lumen
GO:0033198 IDA response to ATP
GO:0034704 TAS calcium channel complex
GO:0044325 TAS ion channel binding
GO:0045862 IDA positive regulation of proteolysis
GO:0045893 IMP positive regulation of transcription, DNA-templated
GO:0055114 IEA oxidation-reduction process
GO:0060314 TAS regulation of ryanodine-sensitive calcium-release channel activity
GO:0060316 TAS positive regulation of ryanodine-sensitive calcium-release channel activity
GO:0070588 IDA calcium ion transmembrane transport
GO:0071277 IDA cellular response to calcium ion
GO:0090316 IDA positive regulation of intracellular protein transport
GO:0097202 IDA activation of cysteine-type endopeptidase activity

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000108337 Asph-006 protein_coding Mus_musculus 0 396
ENSMUST00000084915 Asph-005 protein_coding Mus_musculus 0 396
ENSMUST00000108340 Asph-002 protein_coding Mus_musculus 0 396
ENSMUST00000078139 Asph-001 protein_coding Mus_musculus 0 396
ENSMUST00000108334 Asph-013 protein_coding Mus_musculus 0 351
ENSMUST00000108339 Asph-003 protein_coding Mus_musculus 0 350
ENSMUST00000098275 Asph-018 protein_coding Mus_musculus 0 300
ENSMUST00000038564 Asph-007 protein_coding Mus_musculus 0 298
ENSMUST00000108335 Asph-014 protein_coding Mus_musculus 0 267
ENSMUST00000108333 Asph-008 protein_coding Mus_musculus 0 267
ENSMUST00000124408 Asph-010 processed_transcript Mus_musculus 0 267
ENSMUST00000137375 Asph-012 processed_transcript Mus_musculus 0 255
ENSMUST00000103004 Asph-009 protein_coding Mus_musculus 0 254
ENSMUST00000152526 Asph-011 protein_coding Mus_musculus 0 254
ENSMUST00000152058 Asph-019 processed_transcript Mus_musculus 0 215
ENSMUST00000084912 Asph-017 protein_coding Mus_musculus 2e-33 148
ENSMUST00000131605 Asph-015 protein_coding Mus_musculus 2e-23 115
ENSMUST00000146441 Asph-004 protein_coding Mus_musculus 2e-23 115

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