ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Transcript Info
Description: actinin, alpha 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000542672 ACTN2-201 ENSG00000077522 9606 + 1:236686454-236764620 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; HAoECHUVECENST00000542672
Transcript ID HAoEC HUVEC
ENST00000542672 0.447±0.11 0.022±0.01

Conserved Regions

Not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0002576 TAS platelet degranulation
GO:0005178 TAS integrin binding
GO:0005509 IEA calcium ion binding
GO:0005515 IPI:IEA protein binding
GO:0005576 TAS extracellular region
GO:0005829 TAS cytosol
GO:0005856 NAS cytoskeleton
GO:0005884 TAS actin filament
GO:0005925 IMP focal adhesion
GO:0006936 IEA muscle contraction
GO:0007155 TAS cell adhesion
GO:0007268 TAS synaptic transmission
GO:0007596 TAS blood coagulation
GO:0008092 IDA cytoskeletal protein binding
GO:0008307 TAS structural constituent of muscle
GO:0030017 IEA sarcomere
GO:0030018 IDA Z disc
GO:0030035 IDA microspike assembly
GO:0030049 TAS muscle filament sliding
GO:0030168 TAS platelet activation
GO:0030175 IDA filopodium
GO:0030274 IEA LIM domain binding
GO:0030374 IEA ligand-dependent nuclear receptor transcription coactivator activity
GO:0030375 IEA thyroid hormone receptor coactivator activity
GO:0030864 IEA cortical actin cytoskeleton
GO:0031093 TAS platelet alpha granule lumen
GO:0031143 TAS pseudopodium
GO:0031432 IPI titin binding
GO:0042391 IMP regulation of membrane potential
GO:0042802 IPI identical protein binding
GO:0042981 NAS regulation of apoptotic process
GO:0043197 TAS dendritic spine
GO:0043267 IMP negative regulation of potassium ion transport
GO:0043268 IDA positive regulation of potassium ion transport
GO:0044325 IPI ion channel binding
GO:0046983 IDA protein dimerization activity
GO:0048041 IMP focal adhesion assembly
GO:0051015 IEA actin filament binding
GO:0051289 IDA protein homotetramerization
GO:0051373 IDA FATZ binding
GO:0070062 IDA extracellular vesicular exosome
GO:0070080 IPI titin Z domain binding
GO:1901017 IMP negative regulation of potassium ion transmembrane transporter activity
GO:1901018 IDA positive regulation of potassium ion transmembrane transporter activity
GO:2000009 IMP negative regulation of protein localization to cell surface
GO:2000273 IEA positive regulation of receptor activity
GO:2001141 IEA regulation of RNA biosynthetic process

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000064204 Actn2-001 protein_coding Mus_musculus 0 3650
ENSMUST00000168193 Actn2-201 protein_coding Mus_musculus 0 3642
ENSDART00000001649 actn3b-001 protein_coding Danio_rerio 0 1677
ENSDART00000005682 actn3a-001 protein_coding Danio_rerio 0 1515
ENSMUST00000006626 Actn3-001 protein_coding Mus_musculus 0 1341
ENSDART00000100217 actn1-201 protein_coding Danio_rerio 0 1238
ENSDART00000133740 actn1-002 nonsense_mediated_decay Danio_rerio 0 1238
ENSDART00000140243 actn1-001 protein_coding Danio_rerio 0 1238
ENSMUST00000110616 Actn2-002 protein_coding Mus_musculus 0 614

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