ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Transcript Info

Description: apoptotic peptidase activating factor 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000551964 APAF1-002 ENSG00000120868 9606 + 12:98645141-98733527 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; HAoECHUVECENST00000551964
Transcript ID HAoEC HUVEC
ENST00000551964 6.105±0.44 2.064±1.19

Conserved Regions

Not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000166 TAS nucleotide binding
GO:0001843 IEA neural tube closure
GO:0005515 IPI:IEA protein binding
GO:0005524 IEA ATP binding
GO:0005634 IEA nucleus
GO:0005829 TAS cytosol
GO:0006915 TAS apoptotic process
GO:0006919 IDA activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0007275 IEA multicellular organismal development
GO:0007399 TAS nervous system development
GO:0007420 IEA brain development
GO:0008635 IDA activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c
GO:0008656 NAS cysteine-type endopeptidase activator activity involved in apoptotic process
GO:0030900 IEA forebrain development
GO:0042802 IEA identical protein binding
GO:0042981 TAS:IEA regulation of apoptotic process
GO:0043065 TAS positive regulation of apoptotic process
GO:0043293 TAS:IEA apoptosome
GO:0043531 IEA ADP binding
GO:0051402 IEA neuron apoptotic process
GO:0070062 IDA extracellular vesicular exosome
GO:0072432 TAS response to G1 DNA damage checkpoint signaling
GO:0097190 IEA apoptotic signaling pathway
GO:0097193 TAS intrinsic apoptotic signaling pathway
GO:1902510 IEA regulation of apoptotic DNA fragmentation
GO:2001235 IEA positive regulation of apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000020157 Apaf1-001 protein_coding Mus_musculus 0 4244
ENSMUST00000159110 Apaf1-002 protein_coding Mus_musculus 0 4244
ENSMUST00000162618 Apaf1-003 protein_coding Mus_musculus 0 3976
ENSMUST00000160725 Apaf1-008 retained_intron Mus_musculus 2e-31 143

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