ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Gene Info

Description:
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000038738 Shank1 10090 + 7:44310253-44358351 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000107934 Shank1-002 44312707-44357337 protein_coding
  ENSMUST00000107935 Shank1-003 44312688-44357487 protein_coding
  ENSMUST00000107938 Shank1-001 44310253-44358351 protein_coding
  ENSMUST00000127164 Shank1-007 44350762-44352057 retained_intron
  ENSMUST00000134205 Shank1-006 44336017-44342509 processed_transcript
  ENSMUST00000134470 Shank1-005 44336016-44343738 processed_transcript
  ENSMUST00000154776 Shank1-004 44342135-44351358 retained_intron

Expression Patterns


Heat Map
Numeric Values
Transcript'; C166Tie2+ ECmESENSMUST00000107934ENSMUST00000107935ENSMUST00000107938ENSMUST00000127164ENSMUST00000154776
Transcript ID C166 Tie2+ EC mES
ENSMUST00000107934 0.024±0.00 0.003±0.00 N/A
ENSMUST00000107935 0.041±0.00 0.089±0.00 N/A
ENSMUST00000107938 0.024±0.01 0.028±0.02 0.036±0.01
ENSMUST00000127164 0.116±0.00 0.088±0.00 N/A
ENSMUST00000154776 0.059±0.00 N/A 0.101±0.00

Conserved Regions

Not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005737 IEA cytoplasm
GO:0005886 IDA plasma membrane
GO:0006461 ISS protein complex assembly
GO:0007616 IMP long-term memory
GO:0008022 ISS protein C-terminus binding
GO:0008306 IMP associative learning
GO:0008328 IDA ionotropic glutamate receptor complex
GO:0016020 IEA membrane
GO:0017124 ISS SH3 domain binding
GO:0017146 ISS N-methyl-D-aspartate selective glutamate receptor complex
GO:0030054 IEA cell junction
GO:0030159 IEA receptor signaling complex scaffold activity
GO:0030160 IMP GKAP/Homer scaffold activity
GO:0030425 IDA dendrite
GO:0030534 IEA adult behavior
GO:0031877 ISS somatostatin receptor binding
GO:0032232 IDA negative regulation of actin filament bundle assembly
GO:0032403 ISS protein complex binding
GO:0035176 IMP social behavior
GO:0035255 IPI ionotropic glutamate receptor binding
GO:0035418 IMP protein localization to synapse
GO:0042048 IMP olfactory behavior
GO:0042802 ISS identical protein binding
GO:0043005 IDA neuron projection
GO:0043197 IDA dendritic spine
GO:0045202 IEA synapse
GO:0045211 IDA postsynaptic membrane
GO:0046959 IMP habituation
GO:0050885 IMP neuromuscular process controlling balance
GO:0050894 IEA determination of affect
GO:0060013 IMP righting reflex
GO:0060074 ISS synapse maturation
GO:0060076 IDA excitatory synapse
GO:0060997 IMP dendritic spine morphogenesis
GO:0060999 ISS positive regulation of dendritic spine development
GO:0071532 ISS ankyrin repeat binding
GO:0071625 IMP vocalization behavior
GO:0097110 ISS scaffold protein binding
GO:0097481 IDA neuronal postsynaptic density
GO:2000311 IMP regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity
GO:2000463 IMP positive regulation of excitatory postsynaptic membrane potential

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000060539 shank1 protein_coding Danio_rerio
ENSG00000161681 SHANK1 SH3 and multiple ankyrin repeat domains 1 protein_coding Homo_sapiens

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