ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Transcript Info
Description:
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000018113 Ptgis-001 ENSMUSG00000017969 10090 - 2:167202907-167240604 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; C166Tie2+ ECmESENSMUST00000018113
Transcript ID C166 Tie2+ EC mES
ENSMUST00000018113 145.288±31.90 18.809±13.43 5.658±3.18

Conserved Regions

Not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001516 ISS prostaglandin biosynthetic process
GO:0004497 IEA monooxygenase activity
GO:0005506 IEA iron ion binding
GO:0005515 IEA protein binding
GO:0005615 ISS extracellular space
GO:0005634 ISS nucleus
GO:0005783 ISS endoplasmic reticulum
GO:0005901 ISS caveola
GO:0008116 ISS prostaglandin-I synthase activity
GO:0016021 IEA integral component of membrane
GO:0016705 IEA oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0020037 IBA heme binding
GO:0032088 ISS negative regulation of NF-kappaB transcription factor activity
GO:0035360 ISS positive regulation of peroxisome proliferator activated receptor signaling pathway
GO:0042981 IBA regulation of apoptotic process
GO:0045019 ISS negative regulation of nitric oxide biosynthetic process
GO:0045766 ISS positive regulation of angiogenesis
GO:0050728 ISS negative regulation of inflammatory response
GO:0055114 IEA oxidation-reduction process
GO:0071347 ISS cellular response to interleukin-1
GO:0071354 ISS cellular response to interleukin-6
GO:0071456 ISS cellular response to hypoxia
GO:0097190 IEA apoptotic signaling pathway
GO:1900119 ISS positive regulation of execution phase of apoptosis

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000244043 PTGIS-001 protein_coding Homo_sapiens 0 1474
ENST00000478971 PTGIS-002 processed_transcript Homo_sapiens 0 1062

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