ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Transcript Info
Description:
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000044443 Ank2-001 ENSMUSG00000032826 10090 - 3:126921612-126998462 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; Tie2+ ECmESENSMUST00000044443
Transcript ID Tie2+ EC mES
ENSMUST00000044443 0.201±0.13 0.483±0.10

Conserved Regions

Not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0002027 IMP regulation of heart rate
GO:0003283 IEA atrial septum development
GO:0005200 IEA structural constituent of cytoskeleton
GO:0005515 IPI protein binding
GO:0005622 IMP intracellular
GO:0005737 IDA cytoplasm
GO:0005856 IEA cytoskeleton
GO:0005886 IMP plasma membrane
GO:0005887 IDA integral component of plasma membrane
GO:0006874 IMP cellular calcium ion homeostasis
GO:0007399 IEA nervous system development
GO:0008104 IMP protein localization
GO:0010628 IMP positive regulation of gene expression
GO:0010881 IC regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
GO:0010882 IMP regulation of cardiac muscle contraction by calcium ion signaling
GO:0014704 IDA intercalated disc
GO:0015459 IMP potassium channel regulator activity
GO:0016323 IEA basolateral plasma membrane
GO:0019899 IEA enzyme binding
GO:0019901 IEA protein kinase binding
GO:0030018 IDA Z disc
GO:0030315 IDA T-tubule
GO:0030507 IEA spectrin binding
GO:0030674 IDA protein binding, bridging
GO:0030913 IEA paranodal junction assembly
GO:0031430 IDA M band
GO:0031647 IC regulation of protein stability
GO:0031672 IDA A band
GO:0033292 IMP T-tubule organization
GO:0033365 IEA protein localization to organelle
GO:0034394 IMP protein localization to cell surface
GO:0034613 IMP cellular protein localization
GO:0036309 IMP protein localization to M-band
GO:0036371 IMP protein localization to T-tubule
GO:0042383 IDA sarcolemma
GO:0042981 RCA regulation of apoptotic process
GO:0043005 IEA neuron projection
GO:0043034 IDA costamere
GO:0043268 IMP positive regulation of potassium ion transport
GO:0044325 IPI ion channel binding
GO:0045121 IEA membrane raft
GO:0045211 IEA postsynaptic membrane
GO:0048471 IDA perinuclear region of cytoplasm
GO:0050821 IMP protein stabilization
GO:0051117 IPI ATPase binding
GO:0051279 IEA regulation of release of sequestered calcium ion into cytosol
GO:0051597 IEA response to methylmercury
GO:0051924 IMP regulation of calcium ion transport
GO:0051928 IMP positive regulation of calcium ion transport
GO:0055117 IMP regulation of cardiac muscle contraction
GO:0060048 IMP cardiac muscle contraction
GO:0060307 IEA regulation of ventricular cardiac muscle cell membrane repolarization
GO:0070972 IMP protein localization to endoplasmic reticulum
GO:0072659 IMP protein localization to plasma membrane
GO:0072661 IGI protein targeting to plasma membrane
GO:0086004 IMP regulation of cardiac muscle cell contraction
GO:0086005 IEA ventricular cardiac muscle cell action potential
GO:0086014 IMP atrial cardiac muscle cell action potential
GO:0086015 IMP SA node cell action potential
GO:0086036 IGI regulation of cardiac muscle cell membrane potential
GO:0086066 IMP atrial cardiac muscle cell to AV node cell communication
GO:0086070 IMP SA node cell to atrial cardiac muscle cell communication
GO:0086091 IMP regulation of heart rate by cardiac conduction
GO:1901018 IMP positive regulation of potassium ion transmembrane transporter activity
GO:1901019 IMP regulation of calcium ion transmembrane transporter activity
GO:1901021 IMP positive regulation of calcium ion transmembrane transporter activity
GO:2001257 IMP regulation of cation channel activity
GO:2001259 IMP positive regulation of cation channel activity

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000264366 ANK2-026 protein_coding Homo_sapiens 0 2545
ENST00000280772 ANK3-001 protein_coding Homo_sapiens 0 479
ENST00000355288 ANK3-002 protein_coding Homo_sapiens 0 475
ENST00000357077 ANK2-001 protein_coding Homo_sapiens 0 1613
ENST00000373827 ANK3-004 protein_coding Homo_sapiens 0 475
ENST00000394537 ANK2-002 protein_coding Homo_sapiens 0 2196
ENST00000502701 ANK2-025 retained_intron Homo_sapiens 0 645
ENST00000503271 ANK2-009 protein_coding Homo_sapiens 0 942
ENST00000503366 ANK3-005 protein_coding Homo_sapiens 0 475
ENST00000503423 ANK2-010 protein_coding Homo_sapiens 0 2545
ENST00000504415 ANK2-022 protein_coding Homo_sapiens 0 451
ENST00000504454 ANK2-005 protein_coding Homo_sapiens 0 1613
ENST00000504887 ANK2-018 processed_transcript Homo_sapiens 0 606
ENST00000505342 ANK2-011 protein_coding Homo_sapiens 0 1589
ENST00000506344 ANK2-023 protein_coding Homo_sapiens 0 364
ENST00000506722 ANK2-004 protein_coding Homo_sapiens 0 2196
ENST00000508007 ANK2-019 retained_intron Homo_sapiens 0 459
ENST00000508449 ANK3-022 retained_intron Homo_sapiens 1e-34 150
ENST00000509550 ANK2-006 protein_coding Homo_sapiens 0 3131
ENST00000510275 ANK2-008 protein_coding Homo_sapiens 0 1066
ENST00000514160 ANK2-017 retained_intron Homo_sapiens 0 523
ENST00000514960 ANK2-007 protein_coding Homo_sapiens 0 1858
ENST00000515644 ANK2-016 retained_intron Homo_sapiens 0 446
ENST00000610321 ANK3-034 protein_coding Homo_sapiens 0 460
ENST00000612754 ANK2-201 protein_coding Homo_sapiens 0 1000
ENST00000616444 ANK3-033 protein_coding Homo_sapiens 0 407
ENST00000618374 ANK3-201 protein_coding Homo_sapiens 0 475

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