ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Transcript Info
Description: ankyrin 2, neuronal
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000510275 ANK2-008 ENSG00000145362 9606 + 4:113341833-113381567 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; HAoECHUVECENST00000510275
Transcript ID HAoEC HUVEC
ENST00000510275 0.027±0.00 0.057±0.04

Conserved Regions

Not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0002027 IMP regulation of heart rate
GO:0003283 IMP atrial septum development
GO:0005515 IPI:IEA protein binding
GO:0005622 IGI intracellular
GO:0005829 TAS cytosol
GO:0005886 ISS plasma membrane
GO:0006874 ISS cellular calcium ion homeostasis
GO:0007165 IEA signal transduction
GO:0007411 TAS axon guidance
GO:0010628 IGI positive regulation of gene expression
GO:0010881 IGI regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
GO:0010882 IMP regulation of cardiac muscle contraction by calcium ion signaling
GO:0014704 ISS intercalated disc
GO:0016323 IDA basolateral plasma membrane
GO:0019899 IPI enzyme binding
GO:0019901 IPI protein kinase binding
GO:0030018 ISS Z disc
GO:0030315 ISS T-tubule
GO:0030507 IPI spectrin binding
GO:0030674 ISS protein binding, bridging
GO:0031430 ISS M band
GO:0031647 IC regulation of protein stability
GO:0031672 ISS A band
GO:0033292 ISS T-tubule organization
GO:0033365 IGI protein localization to organelle
GO:0034394 ISS protein localization to cell surface
GO:0034613 IGI cellular protein localization
GO:0036309 ISS protein localization to M-band
GO:0036371 ISS protein localization to T-tubule
GO:0042383 ISS sarcolemma
GO:0043034 ISS costamere
GO:0043268 ISS positive regulation of potassium ion transport
GO:0044325 ISS ion channel binding
GO:0045211 IEA postsynaptic membrane
GO:0050821 ISS protein stabilization
GO:0051117 ISS ATPase binding
GO:0051279 IGI regulation of release of sequestered calcium ion into cytosol
GO:0051924 IGI regulation of calcium ion transport
GO:0051928 ISS positive regulation of calcium ion transport
GO:0055117 IMP regulation of cardiac muscle contraction
GO:0060307 IMP regulation of ventricular cardiac muscle cell membrane repolarization
GO:0070296 TAS sarcoplasmic reticulum calcium ion transport
GO:0070972 IGI protein localization to endoplasmic reticulum
GO:0072659 ISS protein localization to plasma membrane
GO:0086004 IGI regulation of cardiac muscle cell contraction
GO:0086005 IMP ventricular cardiac muscle cell action potential
GO:0086014 IMP atrial cardiac muscle cell action potential
GO:0086015 ISS SA node cell action potential
GO:0086046 TAS membrane depolarization during SA node cell action potential
GO:0086066 ISS atrial cardiac muscle cell to AV node cell communication
GO:0086070 IMP SA node cell to atrial cardiac muscle cell communication
GO:0086091 ISS regulation of heart rate by cardiac conduction
GO:1901018 ISS positive regulation of potassium ion transmembrane transporter activity
GO:1901019 ISS regulation of calcium ion transmembrane transporter activity
GO:1901021 ISS positive regulation of calcium ion transmembrane transporter activity
GO:2001259 ISS positive regulation of cation channel activity

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000182064 Ank2-024 protein_coding Mus_musculus 0 1066
ENSMUST00000044443 Ank2-001 protein_coding Mus_musculus 0 1066
ENSMUST00000182588 Ank2-020 retained_intron Mus_musculus 0 1066
ENSMUST00000182078 Ank2-022 protein_coding Mus_musculus 0 621
ENSMUST00000183075 Ank2-018 retained_intron Mus_musculus 0 479
ENSMUST00000182062 Ank2-002 protein_coding Mus_musculus 0 451
ENSMUST00000182025 Ank2-021 nonsense_mediated_decay Mus_musculus 0 381

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