ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Transcript Info
Description:
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000060989 Sorl1-001 ENSMUSG00000049313 10090 - 9:41964720-42124297 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; C166Tie2+ ECmESENSMUST00000060989
Transcript ID C166 Tie2+ EC mES
ENSMUST00000060989 0.593±0.20 0.041±0.02 0.238±0.09

Conserved Regions

Not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000042 ISS protein targeting to Golgi
GO:0001540 IEA beta-amyloid binding
GO:0005515 IPI protein binding
GO:0005615 IEA extracellular space
GO:0005641 IDA nuclear envelope lumen
GO:0005768 IEA endosome
GO:0005769 ISS early endosome
GO:0005771 IEA multivesicular body
GO:0005783 ISS endoplasmic reticulum
GO:0005794 IEA Golgi apparatus
GO:0005802 ISS trans-Golgi network
GO:0006605 ISS protein targeting
GO:0006622 ISS protein targeting to lysosome
GO:0006869 IEA lipid transport
GO:0006892 ISS post-Golgi vesicle-mediated transport
GO:0006897 IEA endocytosis
GO:0008203 IEA cholesterol metabolic process
GO:0008283 IEA cell proliferation
GO:0014910 IEA regulation of smooth muscle cell migration
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0016477 IEA cell migration
GO:0030169 IEA low-density lipoprotein particle binding
GO:0030306 IEA ADP-ribosylation factor binding
GO:0031985 ISS Golgi cisterna
GO:0032091 ISS negative regulation of protein binding
GO:0032460 ISS negative regulation of protein oligomerization
GO:0034362 IEA low-density lipoprotein particle
GO:0043025 IEA neuronal cell body
GO:0043407 IMP negative regulation of MAP kinase activity
GO:0045053 IMP protein retention in Golgi apparatus
GO:0045732 ISS positive regulation of protein catabolic process
GO:0048471 ISO perinuclear region of cytoplasm
GO:0050768 IMP negative regulation of neurogenesis
GO:0051604 ISS protein maturation
GO:0055037 ISS recycling endosome
GO:0070062 IEA extracellular vesicular exosome
GO:0070863 ISS positive regulation of protein exit from endoplasmic reticulum
GO:1901215 IMP negative regulation of neuron death
GO:1902430 IMP negative regulation of beta-amyloid formation
GO:1902771 IMP positive regulation of choline O-acetyltransferase activity
GO:1902948 IMP negative regulation of tau-protein kinase activity
GO:1902953 ISS positive regulation of ER to Golgi vesicle-mediated transport
GO:1902955 ISS positive regulation of early endosome to recycling endosome transport
GO:1902960 IMP negative regulation of aspartic-type endopeptidase activity involved in amyloid precursor protein catabolic process
GO:1902963 IMP negative regulation of metalloendopeptidase activity involved in amyloid precursor protein catabolic process
GO:1902966 ISS positive regulation of protein localization to early endosome
GO:1902997 IMP negative regulation of neurofibrillary tangle assembly
GO:2001137 ISS positive regulation of endocytic recycling

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000260197 SORL1-001 protein_coding Homo_sapiens 0 8419
ENST00000524633 SORL1-011 retained_intron Homo_sapiens 0 791
ENST00000524873 SORL1-008 retained_intron Homo_sapiens 0 351
ENST00000525532 SORL1-003 protein_coding Homo_sapiens 0 4204
ENST00000527649 SORL1-012 retained_intron Homo_sapiens 0 494
ENST00000527934 SORL1-006 protein_coding Homo_sapiens 0 2844
ENST00000528339 SORL1-009 retained_intron Homo_sapiens 0 832
ENST00000529445 SORL1-007 retained_intron Homo_sapiens 0 575
ENST00000532451 SORL1-002 processed_transcript Homo_sapiens 0 2468
ENST00000532694 SORL1-004 protein_coding Homo_sapiens 0 3753
ENST00000534286 SORL1-005 protein_coding Homo_sapiens 0 3738
ENST00000534754 SORL1-010 retained_intron Homo_sapiens 0 732

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