ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Transcript Info
Description:
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000118100 Rapgef2-001 ENSMUSG00000062232 10090 - 3:79062516-79144977 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; Tie2+ ECENSMUST00000118100
Transcript ID Tie2+ EC
ENSMUST00000118100 1.714±0.00

Conserved Regions

Not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001568 IMP blood vessel development
GO:0001764 IMP neuron migration
GO:0005088 ISS Ras guanyl-nucleotide exchange factor activity
GO:0005096 IEA GTPase activator activity
GO:0005737 ISS cytoplasm
GO:0005770 ISS late endosome
GO:0005886 ISS plasma membrane
GO:0005911 ISS cell-cell junction
GO:0007186 IDA G-protein coupled receptor signaling pathway
GO:0007218 IDA neuropeptide signaling pathway
GO:0008285 IMP negative regulation of cell proliferation
GO:0010976 ISS positive regulation of neuron projection development
GO:0016020 ISS membrane
GO:0017034 ISS Rap guanyl-nucleotide exchange factor activity
GO:0019933 IDA cAMP-mediated signaling
GO:0021591 IMP ventricular system development
GO:0021884 IMP forebrain neuron development
GO:0030165 ISS PDZ domain binding
GO:0030552 ISS cAMP binding
GO:0031175 IMP neuron projection development
GO:0031547 ISS brain-derived neurotrophic factor receptor signaling pathway
GO:0031697 ISS beta-1 adrenergic receptor binding
GO:0032092 IDA positive regulation of protein binding
GO:0032320 ISS positive regulation of Ras GTPase activity
GO:0032486 ISS Rap protein signal transduction
GO:0032854 ISS positive regulation of Rap GTPase activity
GO:0038180 ISS nerve growth factor signaling pathway
GO:0043005 ISS neuron projection
GO:0043025 ISS neuronal cell body
GO:0043234 ISS protein complex
GO:0043950 ISS positive regulation of cAMP-mediated signaling
GO:0045202 ISS synapse
GO:0045860 ISS positive regulation of protein kinase activity
GO:0048022 IMP negative regulation of melanin biosynthetic process
GO:0048167 ISS regulation of synaptic plasticity
GO:0048471 ISS perinuclear region of cytoplasm
GO:0050699 ISS WW domain binding
GO:0050774 IMP negative regulation of dendrite morphogenesis
GO:0061028 ISS establishment of endothelial barrier
GO:0070374 IMP positive regulation of ERK1 and ERK2 cascade
GO:0071320 ISS cellular response to cAMP
GO:0071321 ISS cellular response to cGMP
GO:0071880 ISS adenylate cyclase-activating adrenergic receptor signaling pathway
GO:1901888 ISS regulation of cell junction assembly
GO:1990090 ISS cellular response to nerve growth factor stimulus
GO:2000481 IMP positive regulation of cAMP-dependent protein kinase activity
GO:2000670 IMP positive regulation of dendritic cell apoptotic process
GO:2001214 IMP positive regulation of vasculogenesis
GO:2001224 IMP positive regulation of neuron migration

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000264431 RAPGEF2-001 protein_coding Homo_sapiens 0 5939
ENST00000510253 RAPGEF2-010 protein_coding Homo_sapiens 0 472
ENST00000513816 RAPGEF2-002 retained_intron Homo_sapiens 0 444

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