ANGIOGENES: A knowledge database for angiogenesis

Institute of Cardiovascular Regeneration, Goethe University Frankfurt

Transcript Info
Description:
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENSMUST00000178826 Gclm-201 ENSMUSG00000028124 10090 + 3:122245668-122266435 protein_coding

Expression Patterns


Heat Map
Numeric Values
Transcript'; C166Tie2+ ECmESENSMUST00000178826
Transcript ID C166 Tie2+ EC mES
ENSMUST00000178826 20.163±3.71 15.387±0.52 9.885±4.76

Conserved Regions

Not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004357 ISS glutamate-cysteine ligase activity
GO:0006534 IMP cysteine metabolic process
GO:0006536 ISS glutamate metabolic process
GO:0006749 IMP glutathione metabolic process
GO:0006750 ISS glutathione biosynthetic process
GO:0006979 ISS response to oxidative stress
GO:0008637 IGI apoptotic mitochondrial changes
GO:0017109 IDA glutamate-cysteine ligase complex
GO:0035226 ISS glutamate-cysteine ligase catalytic subunit binding
GO:0035229 IDA positive regulation of glutamate-cysteine ligase activity
GO:0042493 ISS response to drug
GO:0046982 IPI protein heterodimerization activity
GO:0050880 ISS regulation of blood vessel size
GO:0051900 IGI regulation of mitochondrial depolarization
GO:2001237 IGI negative regulation of extrinsic apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENST00000370238 GCLM-001 protein_coding Homo_sapiens 0 1155
ENST00000462183 GCLM-003 processed_transcript Homo_sapiens 3e-16 90
ENST00000467772 GCLM-002 processed_transcript Homo_sapiens 0 726
ENST00000615724 GCLM-201 protein_coding Homo_sapiens 0 859
ENST00000619076 GCLM-202 protein_coding Homo_sapiens 0 652

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