Transcript ID | BECs | HAoEC | HMVEC-D | HUVEC |
---|---|---|---|---|
ENST00000370238 | 3.724±0.00 | 5.843±5.64 | 6.216±0.00 | 3.631±2.73 |
Transcript Info |
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Description: | glutamate-cysteine ligase, modifier subunit | |||||
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Transcript Accession | Transcript Name | Contained in Gene | Tax ID | Strand | Position | Biotype |
ENST00000370238 ![]() |
GCLM-001 |
ENSG00000023909 ![]() |
9606 | - |
1:93885205-93909410 |
protein_coding |
Expression Patterns
|
Conserved Regions |
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Not located within a conserved region. |
Gene Ontology | ||
---|---|---|
GO ID | Evidence Type | GO Description |
GO:0000096 | TAS | sulfur amino acid metabolic process |
GO:0004357 | IMP | glutamate-cysteine ligase activity |
GO:0005829 | NAS | cytosol |
GO:0006534 | IEA | cysteine metabolic process |
GO:0006536 | IDA | glutamate metabolic process |
GO:0006749 | IEA | glutathione metabolic process |
GO:0006750 | IEA | glutathione biosynthetic process |
GO:0006805 | TAS | xenobiotic metabolic process |
GO:0006979 | IDA | response to oxidative stress |
GO:0008637 | IEA | apoptotic mitochondrial changes |
GO:0017109 | IEA | glutamate-cysteine ligase complex |
GO:0034641 | TAS | cellular nitrogen compound metabolic process |
GO:0035226 | IPI | glutamate-cysteine ligase catalytic subunit binding |
GO:0035229 | IEA | positive regulation of glutamate-cysteine ligase activity |
GO:0042493 | IDA | response to drug |
GO:0043524 | IEA | negative regulation of neuron apoptotic process |
GO:0044281 | TAS | small molecule metabolic process |
GO:0046982 | IEA | protein heterodimerization activity |
GO:0050880 | IMP | regulation of blood vessel size |
GO:0051409 | IEA | response to nitrosative stress |
GO:0051900 | IEA | regulation of mitochondrial depolarization |
GO:1901687 | TAS | glutathione derivative biosynthetic process |
GO:2001237 | IEA | negative regulation of extrinsic apoptotic signaling pathway |
Homologs | |||||
ENSEMBL Accession | Gene Name | Biotype | Species | E-Value | Bit Score |
ENSMUST00000029769
![]() |
Gclm-001 | protein_coding | Mus_musculus | 0 | 1190 |
ENSMUST00000178826
![]() |
Gclm-201 | protein_coding | Mus_musculus | 0 | 1155 |
ENSMUST00000176445
![]() |
Gclm-005 | protein_coding | Mus_musculus | 0 | 806 |
ENSMUST00000176761
![]() |
Gclm-004 | retained_intron | Mus_musculus | 0 | 562 |
ENSMUST00000149983
![]() |
Gclm-002 | protein_coding | Mus_musculus | 0 | 532 |
ENSMUST00000137540
![]() |
Gclm-003 | processed_transcript | Mus_musculus | 0 | 337 |